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NCT05024760 · ClinicalTrials.gov registry record · Early Phase 1
Antiseptic Effects on the Dental Implant Internal Surface Microbiome
A Early Phase 1 study of Peri Implantitis and Peri-implant Mucositis, sponsored by Madigan Army Medical Center.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 150
- Enrollment target
- 1
- Study location
NCT05024760: Recruiting Early Phase 1 study of Peri Implantitis and Peri-implant Mucositis, sponsored by Madigan Army Medical Center.
NCT05024760 is a Early Phase 1 study of Peri Implantitis and Peri-implant Mucositis that is actively recruiting participants, run by Madigan Army Medical Center. The registered enrollment target is 150 participants, above the 82-participant average among 4 other Peri Implantitis trials with a reported enrollment target (83% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05024760, a Early Phase 1 study of Peri Implantitis and Peri-implant Mucositis, is actively recruiting participants, sponsored by Madigan Army Medical Center.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 150 participants
- Enrollment target
- 1
- Study location
Study Summary
Soldiers operate in environments that are more likely to lead to oral trauma, risking poor dentition which can directly impact military readiness. Dental restoration can often be accomplished via dental implant insertion. Microbiome-associated complications that result in bone loss, including the micro-leakage of bacterial species proliferating in the dental implant internal cavity, frequently lead to implant failure. Reduction in implant bacterial load may result in a shift of the composition of the microbiome in favor of less pathogenic species, potentially improving dental implant success rates, reducing surgical revisions, and associated cost savings. This study aims to determine how disinfectant gel (hydrogen peroxide or chlorhexidine) insertion into dental implant internal cavities affects implant failure rates, bacterial load and microbiome composition.
Primary Outcome
We will compare the rates of dental implant failure between study arms.
Conditions Studied
Interventions
- DRUG Chlorhexidine
- DRUG Hydrogen Peroxide
Study Locations (1)
Washington
- Madigan Army Medical Center - Tacoma
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2022-07-28 |
| Est. Completion | 2025-11 |
| Phase | Early Phase 1 |
What NCT05024760 shows while recruiting
NCT05024760 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, above the 82-participant average among 4 other Peri Implantitis trials with a reported enrollment target (83% higher).
The record links to 4 conditions, with Peri Implantitis appearing as the primary indexed condition, and to 2 interventions - of which Chlorhexidine is the first listed.
NCT05024760 reports a single indexed study location in Washington.
Frequently Asked Questions
What is clinical trial NCT05024760 about?
NCT05024760 is a clinical study titled "Antiseptic Effects on the Dental Implant Internal Surface Microbiome". Soldiers operate in environments that are more likely to lead to oral trauma, risking poor dentition which can directly impact military readiness. Dental restoration can often be accomplished via dental implant insertion. Microbiome-associated complications that result in bone loss, including the mi...
What is the current status of trial NCT05024760?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 150 participants. The study started on 2022-07-28. Estimated completion is 2025-11.
What conditions does trial NCT05024760 study?
This clinical trial studies the following conditions: Peri Implantitis, Peri-implant Mucositis, Implant Infection, Dental Implant Failed.
What interventions are being tested in trial NCT05024760?
The interventions under investigation include: Chlorhexidine (DRUG), Hydrogen Peroxide (DRUG).
Who is sponsoring clinical trial NCT05024760?
This trial is sponsored by Madigan Army Medical Center, which has 22 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05024760 being conducted?
This trial has 1 study location across Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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