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NCT03384108 · ClinicalTrials.gov registry record · NA
In Vivo Assessment of Glutamine Utilization by Bone Marrow Plasma Cells
A NA study of Healthy, sponsored by Mayo Clinic.
- Recruiting
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT03384108: Recruiting NA study of Healthy, sponsored by Mayo Clinic.
NCT03384108 is a NA study of Healthy that is actively recruiting participants, run by Mayo Clinic. The registered enrollment target is 20 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03384108, a NA study of Healthy, is actively recruiting participants, sponsored by Mayo Clinic.
- RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
This pilot study will first establish the feasibility of an in vivo methodology of assessing the utilization of glutamine into the TCA cycle of normal bone marrow plasma cells from healthy subjects while comparing it to an ex vivo approach
Primary Outcome
The plasma cells obtained from the bone marrow aspiration will be processed to determine the percent of 13-carbon enrichment in the various molecules of the TCA cycle within the plasma cells. The outcomes will be reported as a percentage. E.G. 5% of glutamine is labeled with 13-Carbon; e.g. 4% of glutamate is labeled with 13-carbon etc.
Conditions Studied
Interventions
- OTHER 5-13C-Glutamine
- OTHER Bone marrow aspiration
Study Locations (1)
Minnesota
- Mayo Clinic - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2017-09-01 |
| Est. Completion | 2028-01 |
| Phase | NA |
What NCT03384108 shows while recruiting
NCT03384108 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 2 interventions - of which 5-13C-Glutamine is the first listed.
NCT03384108 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT03384108 about?
NCT03384108 is a clinical study titled "In Vivo Assessment of Glutamine Utilization by Bone Marrow Plasma Cells". This pilot study will first establish the feasibility of an in vivo methodology of assessing the utilization of glutamine into the TCA cycle of normal bone marrow plasma cells from healthy subjects while comparing it to an ex vivo approach
What is the current status of trial NCT03384108?
This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2017-09-01. Estimated completion is 2028-01.
What conditions does trial NCT03384108 study?
This clinical trial studies the following conditions: Healthy.
What interventions are being tested in trial NCT03384108?
The interventions under investigation include: 5-13C-Glutamine (OTHER), Bone marrow aspiration (OTHER).
Who is sponsoring clinical trial NCT03384108?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03384108 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03384108's enrollment target sits among peer trials
20 861st of 1090 higher than 194 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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