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NCT03360071 · ClinicalTrials.gov registry record · Phase 2

A Novel Biologic Therapy for Perennial Allergic Rhinitis

A Phase 2 study, sponsored by Johns Hopkins University.

Completed
Registry status
Phase 2
Development phase
31
Enrollment target

NCT03360071: Completed Phase 2 study, sponsored by Johns Hopkins University.

NCT03360071 is a Phase 2 study that has completed, run by Johns Hopkins University. The registered enrollment target is 31 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (77% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT03360071, a Phase 2 study, has completed, sponsored by Johns Hopkins University.

COMPLETED
Registry status
Phase 2
Development phase
31 participants
Enrollment target

Study Summary

This is a randomized, parallel-group, double-blind, phase 2, single center, proof-of-concept study which will evaluate the effect of a preparation of FDA approved allergens (PMA) used as a sub-cutaneously administered immunotherapy for the management of allergic rhinitis (perennial and seasonal).

Primary Outcome

Change in baseline. TNSS (Total Nasal Symptoms Score) + medication rescue score. TNSS is a scale of 0-12 with 12 being severe. Medication score is also 0-12 with 12 being highest use of medications. Thus DCS ranges from 0-24 (severe).

Interventions

  • DRUG Allergen Immunotherapy Extract
  • DRUG Allergen Immunotherapy Control

Trial Details

FieldValue
Enrollment Target 31 participants
Start Date 2016-12-19
Est. Completion 2018-11-01
Phase Phase 2
Johns Hopkins University

1,448 total trials

What the finished NCT03360071 record still lists

NCT03360071 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 31 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (77% lower).

The record links to 0 conditions, and to 2 interventions - of which Allergen Immunotherapy Extract is the first listed.

NCT03360071 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03360071 about?

NCT03360071 is a clinical study titled "A Novel Biologic Therapy for Perennial Allergic Rhinitis". This is a randomized, parallel-group, double-blind, phase 2, single center, proof-of-concept study which will evaluate the effect of a preparation of FDA approved allergens (PMA) used as a sub-cutaneously administered immunotherapy for the management of allergic rhinitis (perennial and seasonal).

What is the current status of trial NCT03360071?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 31 participants. The study started on 2016-12-19. Estimated completion is 2018-11-01.

What interventions are being tested in trial NCT03360071?

The interventions under investigation include: Allergen Immunotherapy Extract (DRUG), Allergen Immunotherapy Control (DRUG).

Who is sponsoring clinical trial NCT03360071?

This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03360071's enrollment target sits among peer trials

31 1578th of 2000 higher than 419 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03360071, the US trial registry maintained by the National Library of Medicine. NCT03360071 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.