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NCT03354728 · ClinicalTrials.gov registry record · Phase 1

Multi-antigen CMV-Modified Vaccinia Ankara Vaccine in Treating Pediatric Patients With Positive Cytomegalovirus Undergoing Donor Stem Cell Transplant

A Phase 1 study of Cytomegaloviral Infection and Hematopoietic Cell Transplant Recipient, sponsored by City of Hope Medical Center.

Recruiting
Registry status
Phase 1
Development phase
80
Enrollment target
1
Study location

NCT03354728 is a Phase 1 study of Cytomegaloviral Infection and Hematopoietic Cell Transplant Recipient that is actively recruiting participants, run by City of Hope Medical Center. The registered enrollment target is 80 participants, above the 60-participant average among 3 other Cytomegaloviral Infection trials with a reported enrollment target (33% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT03354728, a Phase 1 study of Cytomegaloviral Infection and Hematopoietic Cell Transplant Recipient, is actively recruiting participants, sponsored by City of Hope Medical Center.

RECRUITING
Registry status
Phase 1
Development phase
80 participants
Enrollment target
1
Study location

Study Summary

This phase I/II trial studies the side effects and best dose of multi-antigen cytomegalovirus (CMV)-modified vaccinia ankara vaccine and to see how well it works in treating pediatric patients with positive cytomegalovirus who are undergoing donor stem cell transplant. Multi-antigen CMV-modified vaccinia ankara vaccine may help people resist CMV life-threatening complications.

Interventions

  • OTHER Laboratory Biomarker Analysis
  • BIOLOGICAL Multi-peptide CMV-Modified Vaccinia Ankara Vaccine

Study Locations (1)

California

  • City of Hope Medical Center - Duarte

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2018-05-11
Est. Completion 2026-12-11
Phase Phase 1

Sponsor

City of Hope Medical Center

582 total trials

What the Registry Record Tells You About NCT03354728

The ClinicalTrials.gov registry entry for NCT03354728 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 60-participant average among 3 other Cytomegaloviral Infection trials with a reported enrollment target (33% higher). The listed sponsor is City of Hope Medical Center, which has 582 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Cytomegaloviral Infection appearing as the primary indexed condition, and to 2 interventions - of which Laboratory Biomarker Analysis is the first listed.

NCT03354728 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT03354728 about?

NCT03354728 is a clinical study titled "Multi-antigen CMV-Modified Vaccinia Ankara Vaccine in Treating Pediatric Patients With Positive Cytomegalovirus Undergoing Donor Stem Cell Transplant". This phase I/II trial studies the side effects and best dose of multi-antigen cytomegalovirus (CMV)-modified vaccinia ankara vaccine and to see how well it works in treating pediatric patients with positive cytomegalovirus who are undergoing donor stem cell transplant. Multi-antigen CMV-modified vac...

What is the current status of trial NCT03354728?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 80 participants. The study started on 2018-05-11. Estimated completion is 2026-12-11.

What conditions does trial NCT03354728 study?

This clinical trial studies the following conditions: Cytomegaloviral Infection, Hematopoietic Cell Transplant Recipient.

What interventions are being tested in trial NCT03354728?

The interventions under investigation include: Laboratory Biomarker Analysis (OTHER), Multi-peptide CMV-Modified Vaccinia Ankara Vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT03354728?

This trial is sponsored by City of Hope Medical Center, which has 582 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03354728 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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