Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03334851 · ClinicalTrials.gov registry record · Phase 1
Safety and Tolerability Study Of PF-06835375 In Subjects With Seropositive Systemic Lupus Erythematosus Or Rheumatoid Arthritis
A Phase 1 study of Rheumatoid Arthritis and Systemic Lupus Erythematosus, sponsored by Pfizer.
- Completed
- Registry status
- Phase 1
- Development phase
- 74
- Enrollment target
- 17
- Study locations
NCT03334851 is a Phase 1 study of Rheumatoid Arthritis and Systemic Lupus Erythematosus that has completed, run by Pfizer. The registered enrollment target is 74 participants, below the 4,690-participant average among 197 other Rheumatoid Arthritis trials with a reported enrollment target (98% lower). The trial reports 17 study locations across 7 states.
The verdict
NCT03334851, a Phase 1 study of Rheumatoid Arthritis and Systemic Lupus Erythematosus, has completed, sponsored by Pfizer.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 74 participants
- Enrollment target
- 17
- Study locations
Study Summary
This is a Phase 1 single and multiple dose escalation study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of PF-06835375 in subjects with seropositive SLE or RA. The design is double-blind, sponsor open and placebo controlled. This study will include two parts: Part A and Part B. Part A will consist of single ascending dose cohorts, Part B of multiple ascending dose cohorts. This study will enroll up to a total of approximately 112 subjects at approximately 10 sites.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG PF-06835375
Study Locations (17)
Florida
- Clinical Research of West Florida, Inc. - Clearwater
- Private Practice of Robert W. Levin, MD - Clearwater
- Avail Clinical Research - DeLand
- Omega Research Maitland, LLC - Orlando
- Larkin Hospital - South Miami
- Qps Mra, Llc - South Miami
- Qps-Mra, Llc - South Miami
Alabama
- Pinnacle Research Group, LLC - Anniston
- Pinnacle Research Group, LLC - Anniston
California
- Wallace Rheumatic Studies Center - Beverly Hills
- Prive aftercare - Los Angeles
Maryland
- PAREXEL International - EPCU Baltimore - Baltimore
- Rheumatology Express - Catonsville
Texas
- Metroplex Clinical Research Center - Dallas
- MPP Infusion Centers - Dallas
North Carolina
- Carolina Phase 1 Research, LLC - Raleigh
Pennsylvania
- Altoona Center for Clinical Research - Duncansville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 74 participants |
| Start Date | 2017-11-17 |
| Est. Completion | 2022-02-15 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03334851
The ClinicalTrials.gov registry entry for NCT03334851 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 74 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 4,690-participant average among 197 other Rheumatoid Arthritis trials with a reported enrollment target (98% lower). The listed sponsor is Pfizer, which has 1,845 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Rheumatoid Arthritis appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT03334851 reports 17 study locations spanning 7 distinct geographic areas - top geographies include Florida, Alabama, California.
Frequently Asked Questions
What is clinical trial NCT03334851 about?
NCT03334851 is a clinical study titled "Safety and Tolerability Study Of PF-06835375 In Subjects With Seropositive Systemic Lupus Erythematosus Or Rheumatoid Arthritis". This is a Phase 1 single and multiple dose escalation study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of PF-06835375 in subjects with seropositive SLE or RA. The design is double-blind, sponsor open and placebo controlled. This study will include two parts: Part A ...
What is the current status of trial NCT03334851?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 74 participants. The study started on 2017-11-17. Estimated completion is 2022-02-15.
What conditions does trial NCT03334851 study?
This clinical trial studies the following conditions: Rheumatoid Arthritis, Systemic Lupus Erythematosus.
What interventions are being tested in trial NCT03334851?
The interventions under investigation include: Placebo (DRUG), PF-06835375 (DRUG).
Who is sponsoring clinical trial NCT03334851?
This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03334851 being conducted?
This trial has 17 study locations across Alabama, California, Florida, Maryland, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Rheumatoid Arthritis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Nivolumab in Treating Patients With Autoimmune Disorders and Advanced, Metastatic, or Unresectable Cancer
RECRUITING · Phase 1
-
Study of GS-0151 in Participants With Rheumatoid Arthritis
RECRUITING · Phase 1
-
MAD Study of IA-14069
RECRUITING · Phase 1
-
A Study of AZD0120 in Autoimmune Diseases
RECRUITING · Phase 1
-
Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants
RECRUITING · Phase 1
-
Imaging of Lymphatic Vessels in People with Rheumatoid Arthritis (RA)
RECRUITING · Phase 1
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.