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NCT03323164 · ClinicalTrials.gov registry record · Phase 4
Peripapillary Blood Flow After Use of Anti-glaucoma Medications: An OCT Angiography Study
A Phase 4 study, sponsored by Wills Eye.
- Completed
- Registry status
- Phase 4
- Development phase
- 35
- Enrollment target
NCT03323164: Completed Phase 4 study, sponsored by Wills Eye.
NCT03323164 is a Phase 4 study that has completed, run by Wills Eye. The registered enrollment target is 35 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03323164, a Phase 4 study, has completed, sponsored by Wills Eye.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 35 participants
- Enrollment target
Study Summary
This study evaluates the possible acute changes in peripapillary blood flow after instillation of antiglaucoma medications in patients with primary open angle glaucoma (POAG), normal tension glaucoma (NTG), or ocular hypertension (OHTN) using Optical Coherence Tomography (OCT) angiography.
Primary Outcome
Percent change in peripapillary vessel density detected by OCT (optical coherence tomography) Angiography using spectrum amplitude decorrelation angiography (SSADA) algorithm with the use of topical brimonidine or timolol eye drops to lower eye pressure.
Interventions
- DRUG Timolol Maleate
- DRUG Brimonidine Tartrate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 35 participants |
| Start Date | 2017-07-10 |
| Est. Completion | 2020-05-30 |
| Phase | Phase 4 |
What the finished NCT03323164 record still lists
NCT03323164 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 35 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (93% lower).
The record links to 0 conditions, and to 2 interventions - of which Timolol Maleate is the first listed.
NCT03323164 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03323164 about?
NCT03323164 is a clinical study titled "Peripapillary Blood Flow After Use of Anti-glaucoma Medications: An OCT Angiography Study". This study evaluates the possible acute changes in peripapillary blood flow after instillation of antiglaucoma medications in patients with primary open angle glaucoma (POAG), normal tension glaucoma (NTG), or ocular hypertension (OHTN) using Optical Coherence Tomography (OCT) angiography.
What is the current status of trial NCT03323164?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 35 participants. The study started on 2017-07-10. Estimated completion is 2020-05-30.
What interventions are being tested in trial NCT03323164?
The interventions under investigation include: Timolol Maleate (DRUG), Brimonidine Tartrate (DRUG).
Who is sponsoring clinical trial NCT03323164?
This trial is sponsored by Wills Eye, which has 59 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03323164's enrollment target sits among peer trials
35 1506th of 2000 higher than 481 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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