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NCT03318809 · ClinicalTrials.gov registry record · Phase 1

Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 986 Administered Orally to Healthy Volunteers and Participants With Severely Impaired Renal Function

A Phase 1 study of Heart Failure, sponsored by Amgen.

Completed
Registry status
Phase 1
Development phase
12
Enrollment target
4
Study locations

NCT03318809 is a Phase 1 study of Heart Failure that has completed, run by Amgen. The registered enrollment target is 12 participants, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (99% lower). The trial reports 4 study locations across 4 states.

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The verdict

NCT03318809, a Phase 1 study of Heart Failure, has completed, sponsored by Amgen.

COMPLETED
Registry status
Phase 1
Development phase
12 participants
Enrollment target
4
Study locations

Study Summary

A study to assess the safety, tolerability, and pharmacokinetics of AMG 986 given orally as a single dose to healthy participants and participants with severely impaired kidney function.

Conditions Studied

Heart Failure

Interventions

  • DRUG AMG 986

Study Locations (4)

California

  • Research Site - Tustin

Florida

  • Research Site - Orlando

Minnesota

  • Research Site - Minneapolis

Texas

  • Research Site - San Antonio

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2017-12-12
Est. Completion 2018-04-05
Phase Phase 1

Sponsor

Amgen

558 total trials

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What the Registry Record Tells You About NCT03318809

The ClinicalTrials.gov registry entry for NCT03318809 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (99% lower). The listed sponsor is Amgen, which has 558 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Heart Failure appearing as the primary indexed condition, and to 1 intervention - of which AMG 986 is the first listed.

NCT03318809 reports 4 study locations spanning 4 distinct geographic areas - top geographies include California, Florida, Minnesota.

Frequently Asked Questions

What is clinical trial NCT03318809 about?

NCT03318809 is a clinical study titled "Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 986 Administered Orally to Healthy Volunteers and Participants With Severely Impaired Renal Function". A study to assess the safety, tolerability, and pharmacokinetics of AMG 986 given orally as a single dose to healthy participants and participants with severely impaired kidney function.

What is the current status of trial NCT03318809?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2017-12-12. Estimated completion is 2018-04-05.

What conditions does trial NCT03318809 study?

This clinical trial studies the following conditions: Heart Failure.

What interventions are being tested in trial NCT03318809?

The interventions under investigation include: AMG 986 (DRUG).

Who is sponsoring clinical trial NCT03318809?

This trial is sponsored by Amgen, which has 558 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03318809 being conducted?

This trial has 4 study locations across California, Florida, Minnesota, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.