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NCT03301740 · ClinicalTrials.gov registry record · NA
Ultrafiltration Profiling and Outcomes Among Individuals on Maintenance Hemodialysis
A NA study, sponsored by University of North Carolina, Chapel Hill.
- Completed
- Registry status
- NA
- Development phase
- 34
- Enrollment target
NCT03301740 is a NA study that has completed, run by University of North Carolina, Chapel Hill. The registered enrollment target is 34 participants.
The verdict
NCT03301740, a NA study, has completed, sponsored by University of North Carolina, Chapel Hill.
- COMPLETED
- Registry status
- NA
- Development phase
- 34 participants
- Enrollment target
Study Summary
The rate of fluid removal (ultrafiltration, UF) during hemodialysis (HD) may contribute to cardiovascular morbidity and mortality among individuals receiving maintenance HD. More rapid UF rates are associated with higher morbidity and mortality. Ultrafiltration profiling, the practice of varying UF rates to maximize fluid removal during periods of greatest hydration and plasma oncotic pressures, is one treatment modification that may reduce UF-related harm without necessitating reduction in interdialytic fluid intake or longer HD treatments. To date, UF profiling has not been adequately studied independent of sodium profiling. This study investigates the comparative effect of UF profiling versus non-profiled conventional HD on select cardiovascular and patient-reported outcomes. Participants will complete two phases of UF profiling and two phases of conventional HD and will act as their own controls.
Interventions
- OTHER UF profiling during HD
- OTHER Conventional HD
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 34 participants |
| Start Date | 2018-03-12 |
| Est. Completion | 2018-12-18 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03301740
The ClinicalTrials.gov registry entry for NCT03301740 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 34 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of North Carolina, Chapel Hill, which has 1,109 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which UF profiling during HD is the first listed.
NCT03301740 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03301740 about?
NCT03301740 is a clinical study titled "Ultrafiltration Profiling and Outcomes Among Individuals on Maintenance Hemodialysis". The rate of fluid removal (ultrafiltration, UF) during hemodialysis (HD) may contribute to cardiovascular morbidity and mortality among individuals receiving maintenance HD. More rapid UF rates are associated with higher morbidity and mortality. Ultrafiltration profiling, the practice of varying UF ...
What is the current status of trial NCT03301740?
This trial is currently completed. It is a NA study. The enrollment target is 34 participants. The study started on 2018-03-12. Estimated completion is 2018-12-18.
What interventions are being tested in trial NCT03301740?
The interventions under investigation include: UF profiling during HD (OTHER), Conventional HD (OTHER).
Who is sponsoring clinical trial NCT03301740?
This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.
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