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NCT03284307 · ClinicalTrials.gov registry record · Phase 4
UNderstanding CONSciousness Connectedness and Intraoperative Unresponsiveness Study
A Phase 4 study, sponsored by University of Wisconsin, Madison.
- Completed
- Registry status
- Phase 4
- Development phase
- 35
- Enrollment target
NCT03284307: Completed Phase 4 study, sponsored by University of Wisconsin, Madison.
NCT03284307 is a Phase 4 study that has completed, run by University of Wisconsin, Madison. The registered enrollment target is 35 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03284307, a Phase 4 study, has completed, sponsored by University of Wisconsin, Madison.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 35 participants
- Enrollment target
Study Summary
This study will be a single-site, controlled, unblinded study at the University of Wisconsin to examine changes in the electroencephalogram during anesthesia and waking.
Primary Outcome
The difference in spontaneous EEG slow wave activity over posterior cortex between states of consciousness measured with high-density EEG equipment and reported in spectral power in the delta band (1-4 Hz) at electrode Oz. Disconnected conscious experience (dreaming), connected conscious experience (awareness of the external world), and unconsciousness (no report) was assessed when participants were roused from sedation or sleep.
Interventions
- DRUG Ketamine
- DRUG Midazolam
- DRUG Dexmedetomidine
- DRUG Propofol
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 35 participants |
| Start Date | 2017-08-10 |
| Est. Completion | 2020-03-12 |
| Phase | Phase 4 |
What the finished NCT03284307 record still lists
NCT03284307 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 35 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (93% lower).
The record links to 0 conditions, and to 4 interventions - of which Ketamine is the first listed.
NCT03284307 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03284307 about?
NCT03284307 is a clinical study titled "UNderstanding CONSciousness Connectedness and Intraoperative Unresponsiveness Study". This study will be a single-site, controlled, unblinded study at the University of Wisconsin to examine changes in the electroencephalogram during anesthesia and waking.
What is the current status of trial NCT03284307?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 35 participants. The study started on 2017-08-10. Estimated completion is 2020-03-12.
What interventions are being tested in trial NCT03284307?
The interventions under investigation include: Ketamine (DRUG), Midazolam (DRUG), Dexmedetomidine (DRUG), Propofol (DRUG).
Who is sponsoring clinical trial NCT03284307?
This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03284307's enrollment target sits among peer trials
35 1506th of 2000 higher than 481 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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