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NCT06651580 · ClinicalTrials.gov registry record
Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study
A clinical trial of Chronic Pancreatitis and Recurrent Acute Pancreatitis, sponsored by M.D. Anderson Cancer Center.
- Recruiting
- Registry status
- 1,600
- Enrollment target
- 20
- Study locations
NCT06651580: Recruiting study of Chronic Pancreatitis and Recurrent Acute Pancreatitis, sponsored by M.D. Anderson Cancer Center.
NCT06651580 is a study of Chronic Pancreatitis and Recurrent Acute Pancreatitis that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 1,600 participants, above the 651-participant average among 42 other Chronic Pancreatitis trials with a reported enrollment target (146% higher). The trial reports 20 study locations across 13 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06651580, a study of Chronic Pancreatitis and Recurrent Acute Pancreatitis, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.
- RECRUITING
- Registry status
- 1,600 participants
- Enrollment target
- 20
- Study locations
Study Summary
This clinical trial collects blood, saliva, urine, or stool samples to help identify possible genetic mutations that may increase a person's chance at developing pancreatic cancer. Finding genetic markers among pediatric patients with acute recurrent pancreatitis and chronic pancreatitis may help identify patients who are at risk of pancreatic cancer.
Primary Outcome
Two-sample t-test or Wilcoxon rank-sum test will be used for the continuous/ordinal variables and Pearson Chi-square test for the categorical variables. The variables that suggest differences between ARP and CP (p value \< 0.15) will be included as independent variables in a multivariable logistic regression analysis for CP progression.
Conditions Studied
Interventions
- PROCEDURE Biospecimen Collection
- OTHER Quality-of-Life Assessment
- OTHER Questionnaire Administration
Study Locations (20)
California
- Children's Hospital Los Angeles - Los Angeles
- Cedars Sinai Medical Center - Los Angeles
- UCSF Benioff Children's Hospital Oakland - Oakland
- Stanford Cancer Institute Palo Alto - Palo Alto
Texas
- University of Texas Southwestern/Children's Medical Center - Dallas
- M D Anderson Cancer Center - Houston
- Texas Children's Hospital - Houston
Ohio
- Cincinnati Children's Hospital Medical Center - Cincinnati
- Nationwide Children's Hospital - Columbus
Pennsylvania
- Children's Hospital of Philadelphia - Philadelphia
- Children's Hospital of Pittsburgh of UPMC - Pittsburgh
Colorado
- University of Colorado - Denver
Georgia
- Emory University Hospital/Winship Cancer Institute - Atlanta
Indiana
- Riley Hospital for Children - Indianapolis
Iowa
- University of Iowa/Holden Comprehensive Cancer Center - Iowa City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,600 participants |
| Start Date | 2021-04-01 |
| Est. Completion | 2027-02-02 |
What NCT06651580 shows while recruiting
NCT06651580 is an observational study that tracks outcomes without assigning an intervention. Its 1,600 participants enrollment target places it among the larger protocols in the corpus, above the 651-participant average among 42 other Chronic Pancreatitis trials with a reported enrollment target (146% higher).
The record links to 3 conditions, with Chronic Pancreatitis appearing as the primary indexed condition, and to 3 interventions - of which Biospecimen Collection is the first listed.
NCT06651580 names 20 study sites across 13 states, led by California, Texas, Ohio.
Frequently Asked Questions
What is clinical trial NCT06651580 about?
NCT06651580 is a clinical study titled "Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study". This clinical trial collects blood, saliva, urine, or stool samples to help identify possible genetic mutations that may increase a person's chance at developing pancreatic cancer. Finding genetic markers among pediatric patients with acute recurrent pancreatitis and chronic pancreatitis may help id...
What is the current status of trial NCT06651580?
This trial is currently recruiting. The enrollment target is 1,600 participants. The study started on 2021-04-01. Estimated completion is 2027-02-02.
What conditions does trial NCT06651580 study?
This clinical trial studies the following conditions: Chronic Pancreatitis, Recurrent Acute Pancreatitis, Exocrine Pancreas Carcinoma.
What interventions are being tested in trial NCT06651580?
The interventions under investigation include: Biospecimen Collection (PROCEDURE), Quality-of-Life Assessment (OTHER), Questionnaire Administration (OTHER).
Who is sponsoring clinical trial NCT06651580?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06651580 being conducted?
This trial has 20 study locations across California, Colorado, Georgia, Indiana, Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Pancreatitis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06651580's enrollment target sits among peer trials
1,600 2nd of 42 the highest of 42 other Chronic Pancreatitis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Pancreatitis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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