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COPD-Related Physiology and the Brain
NCT03269721 · View on ClinicalTrials.gov ↗
Study Summary
COPD is the third leading cause of combined morbidity, disability, and mortality in the United States and is often associated with cognitive impairment. The goal of the proposed project is to examine novel pulmonary and vascular physiological mechanisms that contribute to structural brain abnormalities and cognitive dysfunction early in the course of COPD. The project will generate information to ultimately inform the development of interventions to delay or prevent cognitive dysfunction.
Conditions Studied
Interventions
- PROCEDURE Spirometry
- BEHAVIORAL Neuropsychological Assessment
- PROCEDURE Arterial Blood Gas
- PROCEDURE Diffusion Capacity of the Lung for Carbon Monoxide
- DIAGNOSTIC_TEST 6 Minute Walk Test
Study Locations (1)
Iowa
- University of Iowa — Iowa City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 170 participants |
| Start Date | 2017-05-01 |
| Est. Completion | 2025-04-30 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03269721
The ClinicalTrials.gov registry entry for NCT03269721 describes a study currently listed as completed. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 170 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Karin Hoth, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Cognitive Impairment appearing as the primary indexed condition, and to 5 interventions — of which Spirometry is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT03269721 reports 1 study location spanning 1 distinct geographic area — top geographies include Iowa. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT03269721 about?
NCT03269721 is a clinical study titled "COPD-Related Physiology and the Brain". COPD is the third leading cause of combined morbidity, disability, and mortality in the United States and is often associated with cognitive impairment. The goal of the proposed project is to examine novel pulmonary and vascular physiological mechanisms that contribute to structural brain abnormalit...
What is the current status of trial NCT03269721?
This trial is currently completed. The enrollment target is 170 participants. The study started on 2017-05-01. Estimated completion is 2025-04-30.
What conditions does trial NCT03269721 study?
This clinical trial studies the following conditions: Cognitive Impairment, Pulmonary Disease, Chronic Obstructive (COPD). These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT03269721?
The interventions under investigation include: Spirometry (PROCEDURE), Neuropsychological Assessment (BEHAVIORAL), Arterial Blood Gas (PROCEDURE), Diffusion Capacity of the Lung for Carbon Monoxide (PROCEDURE), 6 Minute Walk Test (DIAGNOSTIC_TEST). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT03269721?
This trial is sponsored by Karin Hoth, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT03269721 being conducted?
This trial has 1 study location across Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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