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NCT03269721 · ClinicalTrials.gov registry record
COPD-Related Physiology and the Brain
A clinical trial of Cognitive Impairment and Pulmonary Disease, Chronic Obstructive (COPD), sponsored by Karin Hoth.
- Completed
- Registry status
- 170
- Enrollment target
- 1
- Study location
NCT03269721: Completed study of Cognitive Impairment and Pulmonary Disease, Chronic Obstructive (COPD), sponsored by Karin Hoth.
NCT03269721 is a study of Cognitive Impairment and Pulmonary Disease, Chronic Obstructive (COPD) that has completed, run by Karin Hoth. The registered enrollment target is 170 participants, below the 664-participant average among 105 other Cognitive Impairment trials with a reported enrollment target (74% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03269721, a study of Cognitive Impairment and Pulmonary Disease, Chronic Obstructive (COPD), has completed, sponsored by Karin Hoth.
- COMPLETED
- Registry status
- 170 participants
- Enrollment target
- 1
- Study location
Study Summary
COPD is the third leading cause of combined morbidity, disability, and mortality in the United States and is often associated with cognitive impairment. The goal of the proposed project is to examine novel pulmonary and vascular physiological mechanisms that contribute to structural brain abnormalities and cognitive dysfunction early in the course of COPD. The project will generate information to ultimately inform the development of interventions to delay or prevent cognitive dysfunction.
Primary Outcome
Fractional anisotropy from diffusion weighted imaging will be the primary WM measure
Conditions Studied
Interventions
- PROCEDURE Spirometry
- BEHAVIORAL Neuropsychological Assessment
- PROCEDURE Arterial Blood Gas
- PROCEDURE Diffusion Capacity of the Lung for Carbon Monoxide
- DIAGNOSTIC_TEST 6 Minute Walk Test
Study Locations (1)
Iowa
- University of Iowa - Iowa City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 170 participants |
| Start Date | 2017-05-01 |
| Est. Completion | 2025-04-30 |
What the finished NCT03269721 record still lists
NCT03269721 is an observational study that tracks outcomes without assigning an intervention. The registered 170 participants enrollment target is mid-sized for trials with a published cap, below the 664-participant average among 105 other Cognitive Impairment trials with a reported enrollment target (74% lower).
The record links to 2 conditions, with Cognitive Impairment appearing as the primary indexed condition, and to 5 interventions - of which Spirometry is the first listed.
NCT03269721 reports a single indexed study location in Iowa.
Frequently Asked Questions
What is clinical trial NCT03269721 about?
NCT03269721 is a clinical study titled "COPD-Related Physiology and the Brain". COPD is the third leading cause of combined morbidity, disability, and mortality in the United States and is often associated with cognitive impairment. The goal of the proposed project is to examine novel pulmonary and vascular physiological mechanisms that contribute to structural brain abnormalit...
What is the current status of trial NCT03269721?
This trial is currently completed. The enrollment target is 170 participants. The study started on 2017-05-01. Estimated completion is 2025-04-30.
What conditions does trial NCT03269721 study?
This clinical trial studies the following conditions: Cognitive Impairment, Pulmonary Disease, Chronic Obstructive (COPD).
What interventions are being tested in trial NCT03269721?
The interventions under investigation include: Spirometry (PROCEDURE), Neuropsychological Assessment (BEHAVIORAL), Arterial Blood Gas (PROCEDURE), Diffusion Capacity of the Lung for Carbon Monoxide (PROCEDURE), 6 Minute Walk Test (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT03269721?
This trial is sponsored by Karin Hoth, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03269721 being conducted?
This trial has 1 study location across Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT03269721's enrollment target sits among peer trials
170 30th of 105 higher than 76 of 105 other Cognitive Impairment trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cognitive Impairment trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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