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NCT03245541 · ClinicalTrials.gov registry record · Phase 1

Radiation Therapy in Combination With Durvalumab for People With Pancreatic Cancer

A Phase 1 study of Pancreatic Adenocarcinoma, sponsored by Memorial Sloan Kettering Cancer Center.

Active
Registry status
Phase 1
Development phase
18
Enrollment target
7
Study locations

NCT03245541: Active Phase 1 study of Pancreatic Adenocarcinoma, sponsored by Memorial Sloan Kettering Cancer Center.

NCT03245541 is a Phase 1 study of Pancreatic Adenocarcinoma that is active but no longer recruiting, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 18 participants, below the 99,465-participant average among 62 other Pancreatic Adenocarcinoma trials with a reported enrollment target (100% lower). The trial reports 7 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03245541, a Phase 1 study of Pancreatic Adenocarcinoma, is active but no longer recruiting, sponsored by Memorial Sloan Kettering Cancer Center.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
18 participants
Enrollment target
7
Study locations

Study Summary

The purpose of this study is to find out if combining durvalumab with standard stereotactic ablative radiotherapy (SABR) is an effective treatment for people with locally advanced or borderline resectable pancreatic cancer. The researchers will also look at the safety of the combination treatment and any side effects it causes.

Conditions Studied

Interventions

  • DRUG Durvalumab
  • RADIATION Stereotactic Ablative Body Radiotherapy (SABR)

Study Locations (7)

New York

  • Memorial Sloan Kettering Commack (Limited Protocol Activities) - Commack
  • Memorial Sloan Kettering Westchester (All Protocol Activities) - Harrison
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities) - New York
  • Memorial Sloan Kettering Nassau (Limited Protocol Activities) - Uniondale

New Jersey

  • Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities) - Basking Ridge
  • Memorial Sloan Kettering Monmouth (Limited Protocol Activities) - Middletown
  • Memorial Sloan Kettering Bergen (Limited Protocol Activities) - Montvale

Trial Details

FieldValue
Enrollment Target 18 participants
Start Date 2020-08-14
Est. Completion 2026-09
Phase Phase 1
Memorial Sloan Kettering Cancer Center

1,884 total trials

What the registry record for NCT03245541 still lists

NCT03245541 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 99,465-participant average among 62 other Pancreatic Adenocarcinoma trials with a reported enrollment target (100% lower).

The record links to 1 condition, with Pancreatic Adenocarcinoma appearing as the primary indexed condition, and to 2 interventions - of which Durvalumab is the first listed.

NCT03245541 lists 7 locations in 2 states (New York, New Jersey).

Frequently Asked Questions

What is clinical trial NCT03245541 about?

NCT03245541 is a clinical study titled "Radiation Therapy in Combination With Durvalumab for People With Pancreatic Cancer". The purpose of this study is to find out if combining durvalumab with standard stereotactic ablative radiotherapy (SABR) is an effective treatment for people with locally advanced or borderline resectable pancreatic cancer. The researchers will also look at the safety of the combination treatment an...

What is the current status of trial NCT03245541?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2020-08-14. Estimated completion is 2026-09.

What conditions does trial NCT03245541 study?

This clinical trial studies the following conditions: Pancreatic Adenocarcinoma.

What interventions are being tested in trial NCT03245541?

The interventions under investigation include: Durvalumab (DRUG), Stereotactic Ablative Body Radiotherapy (SABR) (RADIATION).

Who is sponsoring clinical trial NCT03245541?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03245541 being conducted?

This trial has 7 study locations across New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Pancreatic Adenocarcinoma

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT03245541's enrollment target sits among peer trials

18 56th of 62 higher than 6 of 62 other Pancreatic Adenocarcinoma trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Pancreatic Adenocarcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03245541, the US trial registry maintained by the National Library of Medicine. NCT03245541 (small enrollment · multi site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.