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NCT03181334 · ClinicalTrials.gov registry record · NA
The C-SPAN Coalition: Colorectal Cancer Screening and Patient Navigation
A NA study, sponsored by University of Texas Southwestern Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 7,711
- Enrollment target
NCT03181334: Completed NA study, sponsored by University of Texas Southwestern Medical Center.
NCT03181334 is a NA study that has completed, run by University of Texas Southwestern Medical Center. The registered enrollment target is 7,711 participants, above the 1,403-participant average among 58,714 other NA trials with a reported enrollment target (450% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03181334, a NA study, has completed, sponsored by University of Texas Southwestern Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 7,711 participants
- Enrollment target
Study Summary
Participants will be mailed an invitation to complete CRC screening along with a fecal immunochemical test (FIT) kit, containing a 1-sample "Polymedco Over the Counter (OC) Sensor FIT", simplified English/Spanish instructions on performing the test, educational information about colorectal cancer screening and a return mailer with prepaid postage. Processes that will be used to promote screening completion include automated and "live" phone call reminders to encourage completion of FIT testing. Participants will be randomly assigned to 1 of 5 interventions across 3 conditions, described below: 1. Condition 1 (Standard Intervention): * Branch I: Participants assigned to the control condition will receive a FIT kit and the standard invitation letter to participate in free screening. 2. Condition 2 (Time Guideline): * Branch II: Participants will receive a FIT kit and invitation letter to participate in free screening with a 1-week time restriction. * Branch III: Participants will receive a FIT kit and invitation letter to participate in free screening with a 3-week time restriction. 3. Condition 3 (Time Guideline + Incentive): * Branch IV: Participants will receive a FIT kit and invitation letter to participate in free screening requesting they return the kit within 1-week for a "higher" monetary incentive or within 3 weeks for a "lower" (half of the higher) monetary incentive. * Branch V: Participants will receive a FIT kit and invitation letter to participate in free screening requesting they return the kit within 1-week for a "higher" (same as lower in Branch IV) monetary incentive or within 3 weeks for a "lower" (half of the higher) monetary incentive. Participants with a normal test result will receive a personal letter confirming this with invitations to complete a repeat screening in subsequent year(s). Participants receiving an abnormal FIT result will be navigated to complete a diagnostic colonoscopy. Participants continuing in the scre
Primary Outcome
Primary analysis will be proportion of participants returning their kit within 24 days of mailing. We a priori computed sample size required to have 80% power to detect at least an 8% absolute increase in screening between each branch. We planned for 10 pairwise comparisons with a two-sided 0.005 (=0.05/10) significance level and Bonferroni correction. Estimated return rate for the control was 36.5%. Based on these parameters, we estimate requiring at least 1,026 individuals per group. To maximi
Interventions
- BEHAVIORAL Branch I
- BEHAVIORAL Branch II
- BEHAVIORAL Branch III
- BEHAVIORAL Branch IV
- BEHAVIORAL Branch V
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7,711 participants |
| Start Date | 2017-09-05 |
| Est. Completion | 2020-12-31 |
| Phase | NA |
What the finished NCT03181334 record still lists
NCT03181334 is an interventional study that assigns participants to a tested intervention. Its 7,711 participants enrollment target places it among the larger protocols in the corpus, above the 1,403-participant average among 58,714 other NA trials with a reported enrollment target (450% higher).
The record links to 0 conditions, and to 5 interventions - of which Branch I is the first listed.
NCT03181334 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03181334 about?
NCT03181334 is a clinical study titled "The C-SPAN Coalition: Colorectal Cancer Screening and Patient Navigation". Participants will be mailed an invitation to complete CRC screening along with a fecal immunochemical test (FIT) kit, containing a 1-sample "Polymedco Over the Counter (OC) Sensor FIT", simplified English/Spanish instructions on performing the test, educational information about colorectal cancer sc...
What is the current status of trial NCT03181334?
This trial is currently completed. It is a NA study. The enrollment target is 7,711 participants. The study started on 2017-09-05. Estimated completion is 2020-12-31.
What interventions are being tested in trial NCT03181334?
The interventions under investigation include: Branch I (BEHAVIORAL), Branch II (BEHAVIORAL), Branch III (BEHAVIORAL), Branch IV (BEHAVIORAL), Branch V (BEHAVIORAL).
Who is sponsoring clinical trial NCT03181334?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03181334's enrollment target sits among peer trials
7,711 20th of 2000 higher than 1,981 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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