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NCT03173547 · ClinicalTrials.gov registry record · Phase 2
A Six Week Topical Cream Study for Subjects With Ichthyosis Vulgaris
A Phase 2 study, sponsored by Crown Laboratories.
- Completed
- Registry status
- Phase 2
- Development phase
- 80
- Enrollment target
NCT03173547: Completed Phase 2 study, sponsored by Crown Laboratories.
NCT03173547 is a Phase 2 study that has completed, run by Crown Laboratories. The registered enrollment target is 80 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (40% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03173547, a Phase 2 study, has completed, sponsored by Crown Laboratories.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 80 participants
- Enrollment target
Study Summary
The objective of this study is to determine and compare the safety and efficacy of topical 146-9251 cream and vehicle cream applied twice daily for 6 weeks in subjects with moderate to severe ichthyosis vulgaris (IV).
Primary Outcome
Number of participants that show at least a 2 level improvement of overall severity of disease (as measured by IGA score) at 6 weeks. The IGA score is a static evaluation of the overall or "average" degree of severity of a participant's disease, taking into account all of the participant's scaling, erythema, and fissuring in the Treatment Area. IGA was assessed using the following 5-point scale: clear (0), almost clear (1), mild (2), moderate (3), or severe (4).
Interventions
- DRUG Vehicle cream
- DRUG 146-9251 cream
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2017-04-25 |
| Est. Completion | 2019-07-31 |
| Phase | Phase 2 |
What the finished NCT03173547 record still lists
NCT03173547 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (40% lower).
The record links to 0 conditions, and to 2 interventions - of which Vehicle cream is the first listed.
NCT03173547 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03173547 about?
NCT03173547 is a clinical study titled "A Six Week Topical Cream Study for Subjects With Ichthyosis Vulgaris". The objective of this study is to determine and compare the safety and efficacy of topical 146-9251 cream and vehicle cream applied twice daily for 6 weeks in subjects with moderate to severe ichthyosis vulgaris (IV).
What is the current status of trial NCT03173547?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 80 participants. The study started on 2017-04-25. Estimated completion is 2019-07-31.
What interventions are being tested in trial NCT03173547?
The interventions under investigation include: Vehicle cream (DRUG), 146-9251 cream (DRUG).
Who is sponsoring clinical trial NCT03173547?
This trial is sponsored by Crown Laboratories, which has 4 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03173547's enrollment target sits among peer trials
80 842nd of 2000 higher than 1,117 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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