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NCT03169101 · ClinicalTrials.gov registry record
Cognition and Smoking Relapse (HCS)
A clinical trial of Smoking Cessation, sponsored by University of Pennsylvania.
- Completed
- Registry status
- 274
- Enrollment target
- 1
- Study location
NCT03169101: Completed study of Smoking Cessation, sponsored by University of Pennsylvania.
NCT03169101 is a study of Smoking Cessation that has completed, run by University of Pennsylvania. The registered enrollment target is 274 participants, below the 473-participant average among 188 other Smoking Cessation trials with a reported enrollment target (42% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03169101, a study of Smoking Cessation, has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- 274 participants
- Enrollment target
- 1
- Study location
Study Summary
This study tests whether withdrawal-related cognitive deficits increase smoking relapse among HIV-infected (HIV+) vs. HIV-uninfected smokers (HIV-). Adult smokers (N=300; 150 HIV+, 150 HIV-) will complete 2 sessions to assess cognition (24h abstinence vs. smoking-as-usual; order counterbalanced; weeks 0-2). Subjects will then receive smoking cessation counseling and open label transdermal nicotine (weeks 3-12). Outcomes are: 1) cognition; and 2) abstinence rates at the end-of-treatment.
Primary Outcome
Cognitive function will be assessed at the Lab session 1 and lab session 2 visits as well as End of Treatment. Participants will complete measures of executive function, verbal learning and memory and response inhibition. The primary outcome is the change in cognitive function lab session 1, lab session 2, and End of Treatment measured by a composite score (calculated by averaging individual z-scores). Z-scores were calculated using the Stroop interference score (executive function; measured in
Conditions Studied
Interventions
- BEHAVIORAL Behavioral counseling
- DRUG Nicotine patch
Study Locations (1)
Pennsylvania
- Center for Interdisciplinary Research on Nicotine Addiction, University of Pennsylvania - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 274 participants |
| Start Date | 2016-07-01 |
| Est. Completion | 2022-04-25 |
What the finished NCT03169101 record still lists
NCT03169101 is an observational study that tracks outcomes without assigning an intervention. The registered 274 participants enrollment target is mid-sized for trials with a published cap, below the 473-participant average among 188 other Smoking Cessation trials with a reported enrollment target (42% lower).
The record links to 1 condition, with Smoking Cessation appearing as the primary indexed condition, and to 2 interventions - of which Behavioral counseling is the first listed.
NCT03169101 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT03169101 about?
NCT03169101 is a clinical study titled "Cognition and Smoking Relapse (HCS)". This study tests whether withdrawal-related cognitive deficits increase smoking relapse among HIV-infected (HIV+) vs. HIV-uninfected smokers (HIV-). Adult smokers (N=300; 150 HIV+, 150 HIV-) will complete 2 sessions to assess cognition (24h abstinence vs. smoking-as-usual; order counterbalanced; wee...
What is the current status of trial NCT03169101?
This trial is currently completed. The enrollment target is 274 participants. The study started on 2016-07-01. Estimated completion is 2022-04-25.
What conditions does trial NCT03169101 study?
This clinical trial studies the following conditions: Smoking Cessation.
What interventions are being tested in trial NCT03169101?
The interventions under investigation include: Behavioral counseling (BEHAVIORAL), Nicotine patch (DRUG).
Who is sponsoring clinical trial NCT03169101?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03169101 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Smoking Cessation
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03169101's enrollment target sits among peer trials
274 89th of 188 higher than 100 of 188 other Smoking Cessation trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Smoking Cessation trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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