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NCT03144388 · ClinicalTrials.gov registry record · NA

Task-specificity for Locomotor Recovery Following SCI

A NA study of Spinal Cord Injuries, sponsored by Indiana University.

Completed
Registry status
NA
Development phase
17
Enrollment target
1
Study location

NCT03144388 is a NA study of Spinal Cord Injuries that has completed, run by Indiana University. The registered enrollment target is 17 participants, below the 62-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (73% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03144388, a NA study of Spinal Cord Injuries, has completed, sponsored by Indiana University.

COMPLETED
Registry status
NA
Development phase
17 participants
Enrollment target
1
Study location

Study Summary

The primary goal of the proposed study is to identify the contributions of the amount of task-specific practice on locomotor (i.e., walking) recovery in patients with chronic (\> 1 yr) motor incomplete spinal cord injury (iSCI). Consistent with principles of motor learning and exercise physiology, the investigators contend that certain training (i.e., dosage) parameters of physical rehabilitation are critical to mobility outcomes following neurological injury. Specifically, the specificity, amount and intensity of physical interventions (i.e., practice) may influence specific outcomes in the patient population treated. In ambulatory patients with iSCI, there are very few studies that have controlled for or targeted these training variables or their influence on locomotor recovery. Previous work suggests these training parameters may influence locomotor recovery in patients with other neurological disorders (i.e., stroke), although few studies have attempted to delineate similar contributions of in iSCI. Indeed, no studies have carefully controlled the amount of task-specific practice during physical rehabilitation of patients with iSCI, and such interventions are rarely utilized in the clinical setting. The goal of the present study is to delineate the relative contributions of amount of task-specific training on locomotor outcomes in individuals with iSCI. Using a cross-over, randomized clinical trial design, the investigators anticipated non-specific (i.e., non-stepping) training activities would result in smaller improvements as compared to task-specific (stepping) training. The investigators will investigate the effects of such training on walking performance and kinematics, as well as the impairments thought to contribute to walking performance. Successful completion of this project could have an immediate impact on rehabilitation research and treatment of people following iSCI, and may be utilized to treat more subacute patients with iSCI or other acute-onset

Conditions Studied

Interventions

  • PROCEDURE Variable Stepping Training
  • PROCEDURE Variable Non-specific Training

Study Locations (1)

Indiana

  • Rehabilitation Hospital of Indiana - Indianapolis

Trial Details

FieldValue
Enrollment Target 17 participants
Start Date 2017-07-01
Est. Completion 2020-09-30
Phase NA

Sponsor

Indiana University

890 total trials

What the Registry Record Tells You About NCT03144388

The ClinicalTrials.gov registry entry for NCT03144388 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 17 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 62-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (73% lower). The listed sponsor is Indiana University, which has 890 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Spinal Cord Injuries appearing as the primary indexed condition, and to 2 interventions - of which Variable Stepping Training is the first listed.

NCT03144388 reports 1 study location spanning 1 distinct geographic area - top geographies include Indiana.

Frequently Asked Questions

What is clinical trial NCT03144388 about?

NCT03144388 is a clinical study titled "Task-specificity for Locomotor Recovery Following SCI". The primary goal of the proposed study is to identify the contributions of the amount of task-specific practice on locomotor (i.e., walking) recovery in patients with chronic (\> 1 yr) motor incomplete spinal cord injury (iSCI). Consistent with principles of motor learning and exercise physiology, t...

What is the current status of trial NCT03144388?

This trial is currently completed. It is a NA study. The enrollment target is 17 participants. The study started on 2017-07-01. Estimated completion is 2020-09-30.

What conditions does trial NCT03144388 study?

This clinical trial studies the following conditions: Spinal Cord Injuries.

What interventions are being tested in trial NCT03144388?

The interventions under investigation include: Variable Stepping Training (PROCEDURE), Variable Non-specific Training (PROCEDURE).

Who is sponsoring clinical trial NCT03144388?

This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03144388 being conducted?

This trial has 1 study location across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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