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NCT03143270 · ClinicalTrials.gov registry record · Early Phase 1

A Study to Test the Safety and Feasibility of Nivolumab With Drug Eluting Bead Transarterial Chemoembolization in Patients With Liver Cancer

A Early Phase 1 study of Liver Cancer, sponsored by Memorial Sloan Kettering Cancer Center.

Active
Registry status
Early Phase 1
Development phase
20
Enrollment target
9
Study locations

NCT03143270: Active Early Phase 1 study of Liver Cancer, sponsored by Memorial Sloan Kettering Cancer Center.

NCT03143270 is a Early Phase 1 study of Liver Cancer that is active but no longer recruiting, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 20 participants, below the 448-participant average among 78 other Liver Cancer trials with a reported enrollment target (96% lower). The trial reports 9 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03143270, a Early Phase 1 study of Liver Cancer, is active but no longer recruiting, sponsored by Memorial Sloan Kettering Cancer Center.

ACTIVE NOT RECRUITING
Registry status
Early Phase 1
Development phase
20 participants
Enrollment target
9
Study locations

Study Summary

The purpose of the study is to find out the effects of using nivolumab with Drug Eluting Bead Transarterial Chemoembolization (deb-TACE) in the treatment of liver cancer.

Primary Outcome

The percentage of subjects who experience toxicity at each schedule will be calculated. Frequencies of toxicities will be tabulated according to the NCI CTCAE scale (version 4.03).

Conditions Studied

Interventions

  • DRUG Nivolumab
  • DRUG Drug Eluting Bead Transarterial Chemoembolization

Study Locations (9)

New York

  • Memorial Sloan Kettering Cancer Commack - Commack
  • Memorial Sloan Kettering Westchester - Harrison
  • Memorial Sloan Kettering Cancer Center - New York
  • Memorial Sloan Kettering Nassau - Uniondale

New Jersey

  • Memorial Sloan Kettering at Basking Ridge - Basking Ridge
  • Memorial Sloan Kettering Monmouth - Middletown
  • Memorial Sloan Kettering Bergen - Montvale

Missouri

  • Washington University School of Medicine - St Louis

Pennsylvania

  • Abramson Cancer Center at University of Pennsylvania Medical Center - Philadelphia

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2017-04-28
Est. Completion 2026-04
Phase Early Phase 1
Memorial Sloan Kettering Cancer Center

1,884 total trials

What the registry record for NCT03143270 still lists

NCT03143270 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 448-participant average among 78 other Liver Cancer trials with a reported enrollment target (96% lower).

The record links to 1 condition, with Liver Cancer appearing as the primary indexed condition, and to 2 interventions - of which Nivolumab is the first listed.

NCT03143270 lists 9 locations in 4 states (New York, New Jersey, Missouri).

Frequently Asked Questions

What is clinical trial NCT03143270 about?

NCT03143270 is a clinical study titled "A Study to Test the Safety and Feasibility of Nivolumab With Drug Eluting Bead Transarterial Chemoembolization in Patients With Liver Cancer". The purpose of the study is to find out the effects of using nivolumab with Drug Eluting Bead Transarterial Chemoembolization (deb-TACE) in the treatment of liver cancer.

What is the current status of trial NCT03143270?

This trial is currently active not recruiting. It is a Early Phase 1 study. The enrollment target is 20 participants. The study started on 2017-04-28. Estimated completion is 2026-04.

What conditions does trial NCT03143270 study?

This clinical trial studies the following conditions: Liver Cancer.

What interventions are being tested in trial NCT03143270?

The interventions under investigation include: Nivolumab (DRUG), Drug Eluting Bead Transarterial Chemoembolization (DRUG).

Who is sponsoring clinical trial NCT03143270?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03143270 being conducted?

This trial has 9 study locations across Missouri, New Jersey, New York, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Liver Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT03143270's enrollment target sits among peer trials

20 61st of 78 higher than 16 of 78 other Liver Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Liver Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03143270, the US trial registry maintained by the National Library of Medicine. NCT03143270 (small enrollment · multi site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.