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NCT03128229 · ClinicalTrials.gov registry record
Diabetic Kidney Alarm (DKA) Study
A clinical trial of Type 1 Diabetes Mellitus and Diabetic Ketoacidosis, sponsored by University of Colorado, Denver.
- Completed
- Registry status
- 41
- Enrollment target
- 1
- Study location
NCT03128229: Completed study of Type 1 Diabetes Mellitus and Diabetic Ketoacidosis, sponsored by University of Colorado, Denver.
NCT03128229 is a study of Type 1 Diabetes Mellitus and Diabetic Ketoacidosis that has completed, run by University of Colorado, Denver. The registered enrollment target is 41 participants, below the 172-participant average among 112 other Type 1 Diabetes Mellitus trials with a reported enrollment target (76% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03128229, a study of Type 1 Diabetes Mellitus and Diabetic Ketoacidosis, has completed, sponsored by University of Colorado, Denver.
- COMPLETED
- Registry status
- 41 participants
- Enrollment target
- 1
- Study location
Study Summary
The overarching goals of this study are to determine whether tubular dysfunction (elevated urine sodium, bicarbonate and amino acids) and injury (elevated kidney injury molecule 1 \[KIM-1\], neutrophil gelatinase-associated lipocalin \[NGAL\] and matrix metallopeptidase 9 \[MMP9\]) exist in diabetic ketoacidosis (age 3-18), whether it is reversible and whether it is related to uricosuria and copeptin. The investigators propose to study a cohort of youth (ages 3-18, n=40) with T1D who have serum and urine collection at DKA diagnosis and 3-month follow-up.
Primary Outcome
Change in urine Na, HCO3 and amino acids concentrations
Conditions Studied
Study Locations (1)
Colorado
- Children's Hospital Colorado - Aurora
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 41 participants |
| Start Date | 2017-06-01 |
| Est. Completion | 2019-12-13 |
What the finished NCT03128229 record still lists
NCT03128229 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 41 participants, a relatively small participant target, below the 172-participant average among 112 other Type 1 Diabetes Mellitus trials with a reported enrollment target (76% lower).
The record links to 2 conditions, with Type 1 Diabetes Mellitus appearing as the primary indexed condition, and to 0 interventions.
NCT03128229 reports a single indexed study location in Colorado.
Frequently Asked Questions
What is clinical trial NCT03128229 about?
NCT03128229 is a clinical study titled "Diabetic Kidney Alarm (DKA) Study". The overarching goals of this study are to determine whether tubular dysfunction (elevated urine sodium, bicarbonate and amino acids) and injury (elevated kidney injury molecule 1 \[KIM-1\], neutrophil gelatinase-associated lipocalin \[NGAL\] and matrix metallopeptidase 9 \[MMP9\]) exist in diabetic...
What is the current status of trial NCT03128229?
This trial is currently completed. The enrollment target is 41 participants. The study started on 2017-06-01. Estimated completion is 2019-12-13.
What conditions does trial NCT03128229 study?
This clinical trial studies the following conditions: Type 1 Diabetes Mellitus, Diabetic Ketoacidosis.
Who is sponsoring clinical trial NCT03128229?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03128229 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT03128229's enrollment target sits among peer trials
41 59th of 112 higher than 54 of 112 other Type 1 Diabetes Mellitus trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Type 1 Diabetes Mellitus trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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