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NCT03092453 · ClinicalTrials.gov registry record · Phase 1

Dendritic Cell Vaccination in Patients With Advanced Melanoma

A Phase 1 study of Melanoma, sponsored by University of Pennsylvania.

Completed
Registry status
Phase 1
Development phase
5
Enrollment target
1
Study location

NCT03092453 is a Phase 1 study of Melanoma that has completed, run by University of Pennsylvania. The registered enrollment target is 5 participants, below the 707-participant average among 266 other Melanoma trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03092453, a Phase 1 study of Melanoma, has completed, sponsored by University of Pennsylvania.

COMPLETED
Registry status
Phase 1
Development phase
5 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to investigate a method of using dendritic cells (a kind of white blood cell) as a vaccine to stimulate your own immune system to react to your melanoma cells.

Conditions Studied

Interventions

  • DRUG Pembrolizumab
  • BIOLOGICAL Mature dendritic cell (DC) vaccine
  • DRUG Cyclophosphamide 300mg/m^2

Study Locations (1)

Pennsylvania

  • University of Pennsylvania - Philadelphia

Trial Details

FieldValue
Enrollment Target 5 participants
Start Date 2017-05-01
Est. Completion 2023-03-31
Phase Phase 1

Sponsor

University of Pennsylvania

1,423 total trials

What the Registry Record Tells You About NCT03092453

The ClinicalTrials.gov registry entry for NCT03092453 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 5 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 707-participant average among 266 other Melanoma trials with a reported enrollment target (99% lower). The listed sponsor is University of Pennsylvania, which has 1,423 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Melanoma appearing as the primary indexed condition, and to 3 interventions - of which Pembrolizumab is the first listed.

NCT03092453 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT03092453 about?

NCT03092453 is a clinical study titled "Dendritic Cell Vaccination in Patients With Advanced Melanoma". The purpose of this study is to investigate a method of using dendritic cells (a kind of white blood cell) as a vaccine to stimulate your own immune system to react to your melanoma cells.

What is the current status of trial NCT03092453?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 5 participants. The study started on 2017-05-01. Estimated completion is 2023-03-31.

What conditions does trial NCT03092453 study?

This clinical trial studies the following conditions: Melanoma.

What interventions are being tested in trial NCT03092453?

The interventions under investigation include: Pembrolizumab (DRUG), Mature dendritic cell (DC) vaccine (BIOLOGICAL), Cyclophosphamide 300mg/m^2 (DRUG).

Who is sponsoring clinical trial NCT03092453?

This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03092453 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.