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NCT03036904 · ClinicalTrials.gov registry record · Phase 1

Study of Venetoclax Plus DA-EPOCH-R for the Treatment of Aggressive B-Cell Lymphomas

A Phase 1 study, sponsored by Weill Medical College of Cornell University.

Completed
Registry status
Phase 1
Development phase
31
Enrollment target

NCT03036904: Completed Phase 1 study, sponsored by Weill Medical College of Cornell University.

NCT03036904 is a Phase 1 study that has completed, run by Weill Medical College of Cornell University. The registered enrollment target is 31 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (48% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03036904, a Phase 1 study, has completed, sponsored by Weill Medical College of Cornell University.

COMPLETED
Registry status
Phase 1
Development phase
31 participants
Enrollment target

Study Summary

This is a phase I, open label, single-arm, multi-center, dose-finding study of venetoclax in combination with DA-EPOCH-R in patients with aggressive B-Cell Lymphomas.

Primary Outcome

Determination of the maximal tolerated dose (MTD)

Interventions

  • DRUG Venetoclax
  • DRUG Cyclophosphamide
  • DRUG Rituximab
  • DRUG Etoposide
  • DRUG Vincristine Sulfate

Trial Details

FieldValue
Enrollment Target 31 participants
Start Date 2017-02-06
Est. Completion 2021-11-11
Phase Phase 1

What the finished NCT03036904 record still lists

NCT03036904 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 31 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (48% lower).

The record links to 0 conditions, and to 5 interventions - of which Venetoclax is the first listed.

NCT03036904 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03036904 about?

NCT03036904 is a clinical study titled "Study of Venetoclax Plus DA-EPOCH-R for the Treatment of Aggressive B-Cell Lymphomas". This is a phase I, open label, single-arm, multi-center, dose-finding study of venetoclax in combination with DA-EPOCH-R in patients with aggressive B-Cell Lymphomas.

What is the current status of trial NCT03036904?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 31 participants. The study started on 2017-02-06. Estimated completion is 2021-11-11.

What interventions are being tested in trial NCT03036904?

The interventions under investigation include: Venetoclax (DRUG), Cyclophosphamide (DRUG), Rituximab (DRUG), Etoposide (DRUG), Vincristine Sulfate (DRUG).

Who is sponsoring clinical trial NCT03036904?

This trial is sponsored by Weill Medical College of Cornell University, which has 701 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03036904's enrollment target sits among peer trials

31 1322nd of 2000 higher than 669 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03036904, the US trial registry maintained by the National Library of Medicine. NCT03036904 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.