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NCT03008889 · ClinicalTrials.gov registry record · Phase 2

A Feasibility Study of N-acetylcysteine for Self-injurious Behavior in Children With Autism Spectrum Disorder

A Phase 2 study of Autism Spectrum Disorder, sponsored by Emory University.

Completed
Registry status
Phase 2
Development phase
8
Enrollment target
1
Study location

NCT03008889 is a Phase 2 study of Autism Spectrum Disorder that has completed, run by Emory University. The registered enrollment target is 8 participants, below the 135-participant average among 224 other Autism Spectrum Disorder trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03008889, a Phase 2 study of Autism Spectrum Disorder, has completed, sponsored by Emory University.

COMPLETED
Registry status
Phase 2
Development phase
8 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to demonstrate the feasibility of a 9-week, randomized trial of N-acetylcysteine (NAC) compared to placebo in 14 children (age 5 to 12 years) with Autism Spectrum Disorder (ASD) and a moderate level of repetitive self-injurious behavior (SIB). Additional aims are to evaluate the positive predictive value of a screening method to classify children with automatically maintained self-injurious behavior; to evaluate the preliminary efficacy of NAC for reducing repetitive SIB in children with ASD; and to evaluate biomarkers and possible mechanisms of action of NAC in children with ASD.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG N-acetylcysteine

Study Locations (1)

Georgia

  • Marcus Autism Center - Atlanta

Trial Details

FieldValue
Enrollment Target 8 participants
Start Date 2018-07-05
Est. Completion 2019-09-12
Phase Phase 2

Sponsor

Emory University

1,208 total trials

What the Registry Record Tells You About NCT03008889

The ClinicalTrials.gov registry entry for NCT03008889 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 8 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 135-participant average among 224 other Autism Spectrum Disorder trials with a reported enrollment target (94% lower). The listed sponsor is Emory University, which has 1,208 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Autism Spectrum Disorder appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT03008889 reports 1 study location spanning 1 distinct geographic area - top geographies include Georgia.

Frequently Asked Questions

What is clinical trial NCT03008889 about?

NCT03008889 is a clinical study titled "A Feasibility Study of N-acetylcysteine for Self-injurious Behavior in Children With Autism Spectrum Disorder". The purpose of this study is to demonstrate the feasibility of a 9-week, randomized trial of N-acetylcysteine (NAC) compared to placebo in 14 children (age 5 to 12 years) with Autism Spectrum Disorder (ASD) and a moderate level of repetitive self-injurious behavior (SIB). Additional aims are to eval...

What is the current status of trial NCT03008889?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 8 participants. The study started on 2018-07-05. Estimated completion is 2019-09-12.

What conditions does trial NCT03008889 study?

This clinical trial studies the following conditions: Autism Spectrum Disorder.

What interventions are being tested in trial NCT03008889?

The interventions under investigation include: Placebo (DRUG), N-acetylcysteine (DRUG).

Who is sponsoring clinical trial NCT03008889?

This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03008889 being conducted?

This trial has 1 study location across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.