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NCT02998918 · ClinicalTrials.gov registry record · NA

Effects of Short-term Curcumin and Multi-polyphenol Supplementation on the Anti-inflammatory Properties of HDL

A NA study, sponsored by University of South Carolina.

Completed
Registry status
NA
Development phase
21
Enrollment target

NCT02998918: Completed NA study, sponsored by University of South Carolina.

NCT02998918 is a NA study that has completed, run by University of South Carolina. The registered enrollment target is 21 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02998918, a NA study, has completed, sponsored by University of South Carolina.

COMPLETED
Registry status
NA
Development phase
21 participants
Enrollment target

Study Summary

Polyphenol supplements, including curcumin and resveratrol, are known to decrease inflammation, but previous polyphenol supplements were poorly absorbed and thus their effects were reduced. A new phytosome formulation coats the supplements and allows them to be better absorbed. The purpose of this study is to examine the acute (1-hr) and short-term (1-week) effects of two different phytosome-formulated polyphenol supplements on inflammation. The two supplements that will be used are: 1) PolyResveratrol and 2) Curcumin.

Primary Outcome

VCAM-1 expression in HDL plasma will be measured at baseline, and after one week of supplementation for each supplement. Differences in one-week changes in inflammation between each supplement will be compared.

Interventions

  • DIETARY_SUPPLEMENT PolyResveratrol Supplementation
  • DIETARY_SUPPLEMENT Curcumin Supplementation

Trial Details

FieldValue
Enrollment Target 21 participants
Start Date 2016-09
Est. Completion 2020-06
Phase NA
University of South Carolina

157 total trials

What the finished NCT02998918 record still lists

NCT02998918 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 21 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 2 interventions - of which PolyResveratrol Supplementation is the first listed.

NCT02998918 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02998918 about?

NCT02998918 is a clinical study titled "Effects of Short-term Curcumin and Multi-polyphenol Supplementation on the Anti-inflammatory Properties of HDL". Polyphenol supplements, including curcumin and resveratrol, are known to decrease inflammation, but previous polyphenol supplements were poorly absorbed and thus their effects were reduced. A new phytosome formulation coats the supplements and allows them to be better absorbed. The purpose of this s...

What is the current status of trial NCT02998918?

This trial is currently completed. It is a NA study. The enrollment target is 21 participants. The study started on 2016-09. Estimated completion is 2020-06.

What interventions are being tested in trial NCT02998918?

The interventions under investigation include: PolyResveratrol Supplementation (DIETARY_SUPPLEMENT), Curcumin Supplementation (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT02998918?

This trial is sponsored by University of South Carolina, which has 157 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02998918's enrollment target sits among peer trials

21 1762nd of 2000 higher than 233 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02998918, the US trial registry maintained by the National Library of Medicine. NCT02998918 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.