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NCT02997462 · ClinicalTrials.gov registry record
Monocyte Phenotypic Changes in Heart Failure
A clinical trial of Heart Failure and Decompensated Heart Failure, sponsored by University of Michigan.
- Completed
- Registry status
- 60
- Enrollment target
- 1
- Study location
NCT02997462: Completed study of Heart Failure and Decompensated Heart Failure, sponsored by University of Michigan.
NCT02997462 is a study of Heart Failure and Decompensated Heart Failure that has completed, run by University of Michigan. The registered enrollment target is 60 participants, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02997462, a study of Heart Failure and Decompensated Heart Failure, has completed, sponsored by University of Michigan.
- COMPLETED
- Registry status
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
There are many treatments that can improve how long and how well people live with heart failure when they are outside the hospital. However, the investigators know less about how to effectively treat hospitalized heart failure patients so that they do not have to return to the hospital after they go home. Part of the problem is that the investigators don't understand all of the causes of worsening heart failure. Previous studies by other researchers suggest that white blood cells called monocytes are over-active in heart failure. Under normal conditions monocytes help fight infections in the body, but over-active monocytes release chemicals that could cause abnormal function of the heart and blood vessels. The investigators' research group believes that over-active monocytes may be an important reason that heart failure worsens before hospitalization. In this study the investigators will collect blood samples on the day a patient comes into the hospital, the day they return home, and the day they come back to the clinic for a follow-up appointment. The investigators will measure the inflammation in the bloodstream and the activity of monocytes from the patients' blood to see if there are changes in these measurements as heart failure improves. The investigators will also call each patient several times after they return home to ask questions about how they are doing.
Primary Outcome
Cytokine
Conditions Studied
Study Locations (1)
Michigan
- University of Michigan Health System - Ann Arbor
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2011-11 |
| Est. Completion | 2022-06-23 |
What the finished NCT02997462 record still lists
NCT02997462 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (97% lower).
The record links to 2 conditions, with Heart Failure appearing as the primary indexed condition, and to 0 interventions.
NCT02997462 reports a single indexed study location in Michigan.
Frequently Asked Questions
What is clinical trial NCT02997462 about?
NCT02997462 is a clinical study titled "Monocyte Phenotypic Changes in Heart Failure". There are many treatments that can improve how long and how well people live with heart failure when they are outside the hospital. However, the investigators know less about how to effectively treat hospitalized heart failure patients so that they do not have to return to the hospital after they go...
What is the current status of trial NCT02997462?
This trial is currently completed. The enrollment target is 60 participants. The study started on 2011-11. Estimated completion is 2022-06-23.
What conditions does trial NCT02997462 study?
This clinical trial studies the following conditions: Heart Failure, Decompensated Heart Failure.
Who is sponsoring clinical trial NCT02997462?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02997462 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Heart Failure
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02997462's enrollment target sits among peer trials
60 254th of 397 higher than 131 of 397 other Heart Failure trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Heart Failure trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
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-
Integration of Telemedicine and Home-Based Cardiac Rehabilitation: Feasibility, Efficacy, and Adherence
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