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NCT02981381 · ClinicalTrials.gov registry record · NA
Synchronized Transcranial Magnetic Stimulation for PTSD
A NA study of Depression and PTSD, sponsored by Providence VA Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 23
- Enrollment target
- 2
- Study locations
NCT02981381: Completed NA study of Depression and PTSD, sponsored by Providence VA Medical Center.
NCT02981381 is a NA study of Depression and PTSD that has completed, run by Providence VA Medical Center. The registered enrollment target is 23 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (97% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02981381, a NA study of Depression and PTSD, has completed, sponsored by Providence VA Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 23 participants
- Enrollment target
- 2
- Study locations
Study Summary
The investigators propose a small, two-site, sham-controlled pilot study of synchronized Transcranial Magnetic Stimulation (sTMS) in patients with comorbid post-traumatic stress disorder (PTSD) and depression. It is hypothesized that sTMS will be effective for PTSD and mood symptoms.
Primary Outcome
The PTSD checklist (PCL-5) will be used to assess PTSD symptom severity pre- and post-treatment. The change in total PCL-5 score from Baseline (Day 0) to endpoint (PT1) compared between active treatment and sham-controlled groups. If a participant does not complete PT1, last observation carried forward (LOCF) will be used. A 50% reduction in scores from Baseline scores to PT1 indicates clinical response to treatment (active sTMS vs. sham), and remission is defined by a post-treatment score below
Conditions Studied
Interventions
- DEVICE SHAM
- DEVICE NEST-1
- DEVICE NEST-2
Study Locations (2)
Rhode Island
- Providence VAMC - Providence
Vermont
- White River Junction VAMC - White River Junction
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 23 participants |
| Start Date | 2016-10-13 |
| Est. Completion | 2018-10-26 |
| Phase | NA |
What the finished NCT02981381 record still lists
NCT02981381 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 786-participant average among 679 other Depression trials with a reported enrollment target (97% lower).
The record links to 2 conditions, with Depression appearing as the primary indexed condition, and to 3 interventions - of which SHAM is the first listed.
NCT02981381 reports a single indexed study location in Rhode Island, Vermont.
Frequently Asked Questions
What is clinical trial NCT02981381 about?
NCT02981381 is a clinical study titled "Synchronized Transcranial Magnetic Stimulation for PTSD". The investigators propose a small, two-site, sham-controlled pilot study of synchronized Transcranial Magnetic Stimulation (sTMS) in patients with comorbid post-traumatic stress disorder (PTSD) and depression. It is hypothesized that sTMS will be effective for PTSD and mood symptoms.
What is the current status of trial NCT02981381?
This trial is currently completed. It is a NA study. The enrollment target is 23 participants. The study started on 2016-10-13. Estimated completion is 2018-10-26.
What conditions does trial NCT02981381 study?
This clinical trial studies the following conditions: Depression, PTSD.
What interventions are being tested in trial NCT02981381?
The interventions under investigation include: SHAM (DEVICE), NEST-1 (DEVICE), NEST-2 (DEVICE).
Who is sponsoring clinical trial NCT02981381?
This trial is sponsored by Providence VA Medical Center, which has 9 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02981381 being conducted?
This trial has 2 study locations across Rhode Island, Vermont. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02981381's enrollment target sits among peer trials
23 602nd of 679 higher than 76 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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