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NCT02972554 · ClinicalTrials.gov registry record · Phase 4
Does Propranolol Attenuate Inflammatory Responses to a Psychological Stressor?
A Phase 4 study, sponsored by University of North Carolina, Chapel Hill.
- Completed
- Registry status
- Phase 4
- Development phase
- 92
- Enrollment target
NCT02972554 is a Phase 4 study that has completed, run by University of North Carolina, Chapel Hill. The registered enrollment target is 92 participants.
The verdict
NCT02972554, a Phase 4 study, has completed, sponsored by University of North Carolina, Chapel Hill.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 92 participants
- Enrollment target
Study Summary
This randomized, double-blind, placebo-controlled study of propranolol will shed important light on how sympathetic nervous system (SNS) activation influences psychological and inflammatory responses to acute stress. Results from this study will inform both the basic science literature that is attempting to map the physiological mechanisms by which psychological stress may lead to poor mental and physical health, and may also ultimately have therapeutic relevance for individuals who are experiencing high levels of stress that is putting their health at risk. Utilizing a psychopharmacological approach allows for the circumvention of many of the challenges of conducting this research in human populations, and will allow for conclusions regarding causality, given that SNS activation will be experimentally manipulated, rather than relying on correlational measures of SNS activity that are difficult to assess and are not appropriate for asking if SNS activity causes changes in psychology and biology.
Interventions
- OTHER Placebo
- DRUG Propanolol hydrochloride
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 92 participants |
| Start Date | 2016-01-26 |
| Est. Completion | 2017-10-10 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02972554
The ClinicalTrials.gov registry entry for NCT02972554 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 92 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of North Carolina, Chapel Hill, which has 1,109 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT02972554 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02972554 about?
NCT02972554 is a clinical study titled "Does Propranolol Attenuate Inflammatory Responses to a Psychological Stressor?". This randomized, double-blind, placebo-controlled study of propranolol will shed important light on how sympathetic nervous system (SNS) activation influences psychological and inflammatory responses to acute stress. Results from this study will inform both the basic science literature that is attem...
What is the current status of trial NCT02972554?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 92 participants. The study started on 2016-01-26. Estimated completion is 2017-10-10.
What interventions are being tested in trial NCT02972554?
The interventions under investigation include: Placebo (OTHER), Propanolol hydrochloride (DRUG).
Who is sponsoring clinical trial NCT02972554?
This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.
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