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NCT02952508 · ClinicalTrials.gov registry record · Phase 2
Study of Iopofosine I-131 (CLR 131) in Select B-Cell Malignancies (CLOVER-1) With Expansion in Waldenstrom
A Phase 2 study of Multiple Myeloma and Chronic Lymphocytic Leukemia, sponsored by Cellectar Biosciences.
- Active
- Registry status
- Phase 2
- Development phase
- 120
- Enrollment target
- 20
- Study locations
NCT02952508 is a Phase 2 study of Multiple Myeloma and Chronic Lymphocytic Leukemia that is active but no longer recruiting, run by Cellectar Biosciences. The registered enrollment target is 120 participants, below the 546-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (78% lower). The trial reports 20 study locations across 13 states.
The verdict
NCT02952508, a Phase 2 study of Multiple Myeloma and Chronic Lymphocytic Leukemia, is active but no longer recruiting, sponsored by Cellectar Biosciences.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 120 participants
- Enrollment target
- 20
- Study locations
Study Summary
Part A of this study evaluates iopofosine I 131 (CLR 131) in patients with select B-cell malignancies (multiple myeloma( MM), indolent chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL), lymphoplasmacytic lymphoma (LPL)/Waldenstrom Macroglobulinemia (WM), marginal zone lymphoma (MZL), mantle cell lymphoma (MCL), diffuse large B-cell lymphoma (DLBCL), and central nervous system lymphoma (CNSL) who have been previously treated with standard therapy for their underlying malignancy. Part B (CLOVER-WaM) is a pivotal efficacy study evaluating IV administration of iopofosine I 131 in patients with WM that have received at least two prior lines of therapy.
Conditions Studied
Interventions
- DRUG Iopofosine I 131 single dose
- DRUG Iopofosine I 131 multiple dose
- DRUG Iopofosine I 131 fractionated dose
Study Locations (20)
Florida
- Cellectar Biosciences site - Jacksonville
- Cellectar Biosciences site - Miami
- Cellectar Biosciences site - Tampa
New York
- Cellectar Biosciences site - Buffalo
- Cellectar Biosciences site - New York
- Cellectar Biosciences site - Rochester
California
- Cellectar Biosciences site - Los Angeles
- Cellectar Biosciences site - Redlands
Illinois
- Cellectar Biosciences site - Maywood
- Cellectar Biosciences site - Warrenville
Maryland
- Cellectar Biosciences site - Baltimore
- Cellectar Biosciences - Bethesda
District of Columbia
- Cellectar Biosciences site - Washington D.C.
Georgia
- Cellectar Biosciences - Atlanta
Kansas
- Cellectar Biosciences site - Westwood
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2017-07-26 |
| Est. Completion | 2027-12-22 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02952508
The ClinicalTrials.gov registry entry for NCT02952508 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 546-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (78% lower). The listed sponsor is Cellectar Biosciences, which has 10 total studies on file at ClinicalTrials.gov.
The record links to 9 conditions, with Multiple Myeloma appearing as the primary indexed condition, and to 3 interventions - of which Iopofosine I 131 single dose is the first listed.
NCT02952508 reports 20 study locations spanning 13 distinct geographic areas - top geographies include Florida, New York, California.
Frequently Asked Questions
What is clinical trial NCT02952508 about?
NCT02952508 is a clinical study titled "Study of Iopofosine I-131 (CLR 131) in Select B-Cell Malignancies (CLOVER-1) With Expansion in Waldenstrom". Part A of this study evaluates iopofosine I 131 (CLR 131) in patients with select B-cell malignancies (multiple myeloma( MM), indolent chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL), lymphoplasmacytic lymphoma (LPL)/Waldenstrom Macroglobulinemia (WM), marginal zone lymphoma (MZL...
What is the current status of trial NCT02952508?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 120 participants. The study started on 2017-07-26. Estimated completion is 2027-12-22.
What conditions does trial NCT02952508 study?
This clinical trial studies the following conditions: Multiple Myeloma, Chronic Lymphocytic Leukemia, Diffuse Large B Cell Lymphoma, Mantle Cell Lymphoma, Small Lymphocytic Lymphoma.
What interventions are being tested in trial NCT02952508?
The interventions under investigation include: Iopofosine I 131 single dose (DRUG), Iopofosine I 131 multiple dose (DRUG), Iopofosine I 131 fractionated dose (DRUG).
Who is sponsoring clinical trial NCT02952508?
This trial is sponsored by Cellectar Biosciences, which has 10 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02952508 being conducted?
This trial has 20 study locations across California, District of Columbia, Florida, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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