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NCT02940301 · ClinicalTrials.gov registry record · Phase 2

Ibrutinib and Nivolumab in Treating Patients With Relapsed or Refractory Classical Hodgkin Lymphoma

A Phase 2 study of Classical Hodgkin Lymphoma, sponsored by Ohio State University Comprehensive Cancer Center.

Active
Registry status
Phase 2
Development phase
18
Enrollment target
2
Study locations

NCT02940301 is a Phase 2 study of Classical Hodgkin Lymphoma that is active but no longer recruiting, run by Ohio State University Comprehensive Cancer Center. The registered enrollment target is 18 participants, below the 77-participant average among 8 other Classical Hodgkin Lymphoma trials with a reported enrollment target (77% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT02940301, a Phase 2 study of Classical Hodgkin Lymphoma, is active but no longer recruiting, sponsored by Ohio State University Comprehensive Cancer Center.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
18 participants
Enrollment target
2
Study locations

Study Summary

This phase II trial studies how well ibrutinib and nivolumab work in treating patients with classical Hodgkin lymphoma that has come back or has not responded to treatment. Ibrutinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as nivolumab, may block cancer growth in different ways by targeting certain cells. Giving ibrutinib and nivolumab may work better in treating patients with classical Hodgkin lymphoma.

Conditions Studied

Interventions

  • OTHER Laboratory Biomarker Analysis
  • BIOLOGICAL Nivolumab
  • DRUG Ibrutinib

Study Locations (2)

Georgia

  • Winship Cancer Center of Emory University - Atlanta

Ohio

  • Ohio State University Comprehensive Cancer Center - Columbus

Trial Details

FieldValue
Enrollment Target 18 participants
Start Date 2016-12-20
Est. Completion 2026-08-15
Phase Phase 2

What the Registry Record Tells You About NCT02940301

The ClinicalTrials.gov registry entry for NCT02940301 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 18 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 77-participant average among 8 other Classical Hodgkin Lymphoma trials with a reported enrollment target (77% lower). The listed sponsor is Ohio State University Comprehensive Cancer Center, which has 341 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Classical Hodgkin Lymphoma appearing as the primary indexed condition, and to 3 interventions - of which Laboratory Biomarker Analysis is the first listed.

NCT02940301 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Georgia, Ohio.

Frequently Asked Questions

What is clinical trial NCT02940301 about?

NCT02940301 is a clinical study titled "Ibrutinib and Nivolumab in Treating Patients With Relapsed or Refractory Classical Hodgkin Lymphoma". This phase II trial studies how well ibrutinib and nivolumab work in treating patients with classical Hodgkin lymphoma that has come back or has not responded to treatment. Ibrutinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, su...

What is the current status of trial NCT02940301?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 18 participants. The study started on 2016-12-20. Estimated completion is 2026-08-15.

What conditions does trial NCT02940301 study?

This clinical trial studies the following conditions: Classical Hodgkin Lymphoma.

What interventions are being tested in trial NCT02940301?

The interventions under investigation include: Laboratory Biomarker Analysis (OTHER), Nivolumab (BIOLOGICAL), Ibrutinib (DRUG).

Who is sponsoring clinical trial NCT02940301?

This trial is sponsored by Ohio State University Comprehensive Cancer Center, which has 341 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02940301 being conducted?

This trial has 2 study locations across Georgia, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.