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NCT02924883 · ClinicalTrials.gov registry record · Phase 2

A Study to Evaluate the Efficacy and Safety of Trastuzumab Emtansine in Combination With Atezolizumab or Atezolizumab-Placebo in Participants With Human Epidermal Growth Factor-2 (HER2) Positive Locally Advanced or Metastatic Breast Cancer (BC) Who Received Prior Trastuzumab and Taxane Based Therapy

A Phase 2 study, sponsored by Hoffmann-La Roche.

Completed
Registry status
Phase 2
Development phase
202
Enrollment target

NCT02924883 is a Phase 2 study that has completed, run by Hoffmann-La Roche. The registered enrollment target is 202 participants.

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The verdict

NCT02924883, a Phase 2 study, has completed, sponsored by Hoffmann-La Roche.

COMPLETED
Registry status
Phase 2
Development phase
202 participants
Enrollment target

Study Summary

This Phase II, double-blind, randomized, placebo-controlled multicenter study will investigate the efficacy and safety of trastuzumab emtansine in combination with atezolizumab or atezolizumab-placebo in participants with HER2-positive locally advanced or metastatic BC who have received prior trastuzumab and taxane based therapy, either alone or in combination, and/or who have progressed within 6 months after completing adjuvant therapy.

Interventions

  • DRUG Atezolizumab
  • OTHER Placebo
  • DRUG Trastuzumab emtansine

Trial Details

FieldValue
Enrollment Target 202 participants
Start Date 2016-09-26
Est. Completion 2020-02-06
Phase Phase 2

Sponsor

Hoffmann-La Roche

909 total trials

What the Registry Record Tells You About NCT02924883

The ClinicalTrials.gov registry entry for NCT02924883 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 202 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Hoffmann-La Roche, which has 909 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Atezolizumab is the first listed.

NCT02924883 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02924883 about?

NCT02924883 is a clinical study titled "A Study to Evaluate the Efficacy and Safety of Trastuzumab Emtansine in Combination With Atezolizumab or Atezolizumab-Placebo in Participants With Human Epidermal Growth Factor-2 (HER2) Positive Locally Advanced or Metastatic Breast Cancer (BC) Who Received Prior Trastuzumab and Taxane Based Therapy". This Phase II, double-blind, randomized, placebo-controlled multicenter study will investigate the efficacy and safety of trastuzumab emtansine in combination with atezolizumab or atezolizumab-placebo in participants with HER2-positive locally advanced or metastatic BC who have received prior trastu...

What is the current status of trial NCT02924883?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 202 participants. The study started on 2016-09-26. Estimated completion is 2020-02-06.

What interventions are being tested in trial NCT02924883?

The interventions under investigation include: Atezolizumab (DRUG), Placebo (OTHER), Trastuzumab emtansine (DRUG).

Who is sponsoring clinical trial NCT02924883?

This trial is sponsored by Hoffmann-La Roche, which has 909 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.