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NCT02886065 · ClinicalTrials.gov registry record · Phase 1

A Study of PVX-410, a Cancer Vaccine, and Citarinostat +/- Lenalidomide for Smoldering MM

A Phase 1 study of Smoldering Multiple Myeloma, sponsored by Massachusetts General Hospital.

Active
Registry status
Phase 1
Development phase
19
Enrollment target
6
Study locations

NCT02886065 is a Phase 1 study of Smoldering Multiple Myeloma that is active but no longer recruiting, run by Massachusetts General Hospital. The registered enrollment target is 19 participants, below the 799-participant average among 20 other Smoldering Multiple Myeloma trials with a reported enrollment target (98% lower). The trial reports 6 study locations across 4 states.

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The verdict

NCT02886065, a Phase 1 study of Smoldering Multiple Myeloma, is active but no longer recruiting, sponsored by Massachusetts General Hospital.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
19 participants
Enrollment target
6
Study locations

Study Summary

This research study is studying a targeted therapy as a possible treatment for Smoldering Multiple Myeloma. The following intervention will be involved in this study: * Lenalidomide * Citarinostat (CC-96241) * PVX-410

Interventions

  • DRUG Lenalidomide
  • DRUG Hiltonol
  • BIOLOGICAL PVX-410
  • DRUG Citarinostat

Study Locations (6)

Massachusetts

  • Massachusetts General Hospital - Boston
  • Beth Israel Deaconess Medical Center - Boston
  • Dana-Farber Cancer Institute - Boston

New York

  • Weill Cornell Medical College - New York

North Carolina

  • Duke University Medical Center - Durham

Ohio

  • University Hospital of Cleveland- Seidman Cancer Center - Cleveland

Trial Details

FieldValue
Enrollment Target 19 participants
Start Date 2017-03-07
Est. Completion 2026-09-15
Phase Phase 1

Sponsor

Massachusetts General Hospital

2,032 total trials

What the Registry Record Tells You About NCT02886065

The ClinicalTrials.gov registry entry for NCT02886065 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 19 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 799-participant average among 20 other Smoldering Multiple Myeloma trials with a reported enrollment target (98% lower). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Smoldering Multiple Myeloma appearing as the primary indexed condition, and to 4 interventions - of which Lenalidomide is the first listed.

NCT02886065 reports 6 study locations spanning 4 distinct geographic areas - top geographies include Massachusetts, New York, North Carolina.

Frequently Asked Questions

What is clinical trial NCT02886065 about?

NCT02886065 is a clinical study titled "A Study of PVX-410, a Cancer Vaccine, and Citarinostat +/- Lenalidomide for Smoldering MM". This research study is studying a targeted therapy as a possible treatment for Smoldering Multiple Myeloma. The following intervention will be involved in this study: * Lenalidomide * Citarinostat (CC-96241) * PVX-410

What is the current status of trial NCT02886065?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 19 participants. The study started on 2017-03-07. Estimated completion is 2026-09-15.

What conditions does trial NCT02886065 study?

This clinical trial studies the following conditions: Smoldering Multiple Myeloma.

What interventions are being tested in trial NCT02886065?

The interventions under investigation include: Lenalidomide (DRUG), Hiltonol (DRUG), PVX-410 (BIOLOGICAL), Citarinostat (DRUG).

Who is sponsoring clinical trial NCT02886065?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02886065 being conducted?

This trial has 6 study locations across Massachusetts, New York, North Carolina, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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