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NCT02863172 · ClinicalTrials.gov registry record
Molecular Basis for Variations in Hereditary Colorectal Cancer Syndromes
A clinical trial of Hereditary Colorectal Cancer Syndrome, sponsored by M.D. Anderson Cancer Center.
- Recruiting
- Registry status
- 2,000
- Enrollment target
- 1
- Study location
NCT02863172: Recruiting study of Hereditary Colorectal Cancer Syndrome, sponsored by M.D. Anderson Cancer Center.
NCT02863172 is a study of Hereditary Colorectal Cancer Syndrome that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 2,000 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02863172, a study of Hereditary Colorectal Cancer Syndrome, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.
- RECRUITING
- Registry status
- 2,000 participants
- Enrollment target
- 1
- Study location
Study Summary
Objectives: 1. To examine the variations in clinical features, survival outcomes, family history, and health behavior among proband patients who are known or suspected to have a hereditary colorectal cancer syndrome 2. To compare the clinical features, survival outcomes, and health behavior of the proband vs. his/her family members who may or may not be affected by the hereditary colorectal cancer syndrome 3. To explore for correlations between germline genetic variations in both the probands and family members with observed variations in the overall disease phenotype across probands and kindreds, within a given syndrome. Disease phenotype is defined to include: (1) clinicopathologic features including patient demographics and oncologic outcomes; (2) clinical manifestations of disease including the timing, spectrum and severity of CRC and extracolonic cancers. Genetic variations may include the specific codon mutated, the type of mutation and sequence alteration (e.g. nonsense, missense etc), chromosomal/gene copy number changes, and gene polymorphisms. 4. To explore for correlations between germline genetic variations in both the probands and family members with observed variations in somatic CRC tumor biology, including tumor pathology and other tumor molecular markers
Primary Outcome
Comparison made using 1-way ANOVA or Chi-squared tests.
Conditions Studied
Interventions
- BEHAVIORAL Questionnaires
- PROCEDURE Blood Draw/Saliva Sample
Study Locations (1)
Texas
- University of Texas MD Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,000 participants |
| Start Date | 2012-05-22 |
| Est. Completion | 2027-05-30 |
What NCT02863172 shows while recruiting
NCT02863172 is an observational study that tracks outcomes without assigning an intervention. Its 2,000 participants enrollment target places it among the larger protocols in the corpus.
The record links to 1 condition, with Hereditary Colorectal Cancer Syndrome appearing as the primary indexed condition, and to 2 interventions - of which Questionnaires is the first listed.
NCT02863172 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT02863172 about?
NCT02863172 is a clinical study titled "Molecular Basis for Variations in Hereditary Colorectal Cancer Syndromes". Objectives: 1. To examine the variations in clinical features, survival outcomes, family history, and health behavior among proband patients who are known or suspected to have a hereditary colorectal cancer syndrome 2. To compare the clinical features, survival outcomes, and health behavior of the ...
What is the current status of trial NCT02863172?
This trial is currently recruiting. The enrollment target is 2,000 participants. The study started on 2012-05-22. Estimated completion is 2027-05-30.
What conditions does trial NCT02863172 study?
This clinical trial studies the following conditions: Hereditary Colorectal Cancer Syndrome.
What interventions are being tested in trial NCT02863172?
The interventions under investigation include: Questionnaires (BEHAVIORAL), Blood Draw/Saliva Sample (PROCEDURE).
Who is sponsoring clinical trial NCT02863172?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02863172 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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