Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02851511 · ClinicalTrials.gov registry record · NA
Augmenting Cognitive Training In Older Adults
A NA study, sponsored by University of Florida.
- Completed
- Registry status
- NA
- Development phase
- 379
- Enrollment target
NCT02851511 is a NA study that has completed, run by University of Florida. The registered enrollment target is 379 participants.
The verdict
NCT02851511, a NA study, has completed, sponsored by University of Florida.
- COMPLETED
- Registry status
- NA
- Development phase
- 379 participants
- Enrollment target
Study Summary
A two-phase adaptive randomized clinical trial will examine the individual and combined impact of pairing cognitive training with transcranial direct current stimulation (tDCS). tDCS is a method of non-invasive brain stimulation that directly stimulates brain regions involved in active cognitive function and could enhance neural plasticity when paired with a training task. We will compare changes in cognitive and brain function resulting from CT and ET combined with tDCS using a comprehensive neurocognitive, clinical, and multimodal neuroimaging assessment of brain structure, function, and metabolic state. Functional magnetic resonance imaging (FMRI) will be used to assess brain response during working memory, attention, and memory encoding; the active cognitive abilities trained by CT. Proton magnetic resonance spectroscopy (MRS) will assess cerebral metabolites, including GABA concentrations sensitive to neural plasticity. We hypothesize that: 1) tDCS will enhance neurocognitive function, brain function, and functional outcomes from CT, with combined CT and tDCS providing the most benefit; 2) Effects of tDCS on CT will be maintained up to 12 months following training, and 3) Neuroimaging biomarkers of cerebral metabolism, neural plasticity (GABA concentrations) and functional brain response (FMRI) during resting vs. active cognitive tasks will predict individual response to tDCS.
Interventions
- BEHAVIORAL Cognitive Training
- DEVICE tDCS (active stimulation)
- DEVICE tDCS (sham stimulation)
- BEHAVIORAL Educational Training
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 379 participants |
| Start Date | 2017-08-08 |
| Est. Completion | 2022-04-30 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02851511
The ClinicalTrials.gov registry entry for NCT02851511 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 379 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Florida, which has 1,106 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 4 interventions - of which Cognitive Training is the first listed.
NCT02851511 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02851511 about?
NCT02851511 is a clinical study titled "Augmenting Cognitive Training In Older Adults". A two-phase adaptive randomized clinical trial will examine the individual and combined impact of pairing cognitive training with transcranial direct current stimulation (tDCS). tDCS is a method of non-invasive brain stimulation that directly stimulates brain regions involved in active cognitive fun...
What is the current status of trial NCT02851511?
This trial is currently completed. It is a NA study. The enrollment target is 379 participants. The study started on 2017-08-08. Estimated completion is 2022-04-30.
What interventions are being tested in trial NCT02851511?
The interventions under investigation include: Cognitive Training (BEHAVIORAL), tDCS (active stimulation) (DEVICE), tDCS (sham stimulation) (DEVICE), Educational Training (BEHAVIORAL).
Who is sponsoring clinical trial NCT02851511?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.