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NCT02779478 · ClinicalTrials.gov registry record
Evaluation Of The Lung Microbiome In NTM Bronchiectasis
A clinical trial of Bronchiectasis and Nontuberculous Mycobacteria, sponsored by NYU Langone Health.
- Recruiting
- Registry status
- 1,000
- Enrollment target
- 1
- Study location
NCT02779478: Recruiting study of Bronchiectasis and Nontuberculous Mycobacteria, sponsored by NYU Langone Health.
NCT02779478 is a study of Bronchiectasis and Nontuberculous Mycobacteria that is actively recruiting participants, run by NYU Langone Health. The registered enrollment target is 1,000 participants, above the 311-participant average among 13 other Bronchiectasis trials with a reported enrollment target (222% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02779478, a study of Bronchiectasis and Nontuberculous Mycobacteria, is actively recruiting participants, sponsored by NYU Langone Health.
- RECRUITING
- Registry status
- 1,000 participants
- Enrollment target
- 1
- Study location
Study Summary
A biomarker cohort study design is proposed to study whether specific airway microbiota alterations are associated with pulmonary Non-tuberculous mycobacteria (NTM) disease. In a cohort of 200 subjects suspected of having pulmonary NTM disease, the investigators will evaluate the airway microbiome using an aliquot of the induced sputum and upper airway samples. Since induced sputum may reflect different regions of the upper/lower airways, the investigators will evaluate the upper and lower airway microbiome in a subgroup (case-control group) of patients using samples obtained through upper airway sampling and bronchoscopy, respectively.
Primary Outcome
Investigators will use sputum samples and brushed samples from areas of the upper airway from a cohort of 200 subjects with chronic cough and pulmonary infiltrates or airway abnormalities in whom NTM disease was suspected. Cultures positive for NTM (cases) will be compared to those with culture negatives (controls). Bacterial load by quantitative polymerase chain reaction (qPCR) will be used to characterize microbiome by high throughput sequencing looking for microbial biomarkers associated with
Conditions Studied
Interventions
- PROCEDURE Bronchoscopy
Study Locations (1)
New York
- New York University School of Medicine - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,000 participants |
| Start Date | 2014-10-01 |
| Est. Completion | 2031-07 |
What NCT02779478 shows while recruiting
NCT02779478 is an observational study that tracks outcomes without assigning an intervention. Its 1,000 participants enrollment target places it among the larger protocols in the corpus, above the 311-participant average among 13 other Bronchiectasis trials with a reported enrollment target (222% higher).
The record links to 2 conditions, with Bronchiectasis appearing as the primary indexed condition, and to 1 intervention - of which Bronchoscopy is the first listed.
NCT02779478 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT02779478 about?
NCT02779478 is a clinical study titled "Evaluation Of The Lung Microbiome In NTM Bronchiectasis". A biomarker cohort study design is proposed to study whether specific airway microbiota alterations are associated with pulmonary Non-tuberculous mycobacteria (NTM) disease. In a cohort of 200 subjects suspected of having pulmonary NTM disease, the investigators will evaluate the airway microbiome u...
What is the current status of trial NCT02779478?
This trial is currently recruiting. The enrollment target is 1,000 participants. The study started on 2014-10-01. Estimated completion is 2031-07.
What conditions does trial NCT02779478 study?
This clinical trial studies the following conditions: Bronchiectasis, Nontuberculous Mycobacteria.
What interventions are being tested in trial NCT02779478?
The interventions under investigation include: Bronchoscopy (PROCEDURE).
Who is sponsoring clinical trial NCT02779478?
This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02779478 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Bronchiectasis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02779478's enrollment target sits among peer trials
1,000 2nd of 13 the highest of 13 other Bronchiectasis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Bronchiectasis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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