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NCT02774356 · ClinicalTrials.gov registry record
Testing Native Language Neural Commitment at the Subcortical Level
A clinical trial, sponsored by University of Minnesota.
- Completed
- Registry status
- 36
- Enrollment target
NCT02774356: Completed study, sponsored by University of Minnesota.
NCT02774356 is a clinical trial that has completed, run by University of Minnesota. The registered enrollment target is 36 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02774356 has completed, sponsored by University of Minnesota.
- COMPLETED
- Registry status
- 36 participants
- Enrollment target
Study Summary
This mentored student research project is funded by the Graduate Research Partnership Program with a projected timeline for data collection in the summer of 2015. Previous research has shown that language experience alters the way the human brain processes speech information. This phenomenon takes place very early in life and is referred to as Native Language Neural Commitment. For instance, as the Japanese language does not have the l-r speech sound contrast, Japanese infants start to show difficulty in hearing differences between the English l and r sounds at 12 months of age but not when they were at 6 months old. Learning the l-r distinction later in life proves to be very difficult for the Japanese school students and adults. Brain imaging studies have further revealed specific brain regions that are changed by language learning. But the evidence in support of the Native Language Neural Commitment theory is based on cortical-level measures. The proposed study extends the measurement to the subcortical level at the brainstem. The target language that the investigators are interested in studying is Mandarin Chinese, which is known for its use of lexical tones to express different words. For instance, the Chinese syllable "ma" means "mother" when it is spoken with a flat tone, and it means "hemp" when spoken with a rising tone. English, by contrast, does not employ lexical tones, and it is considered a non-tonal language. Does the Chinese learning experience fundamental change the way that pitch information is coded in the human brain? Does it happen at both cortical and subcortical levels? Previous research has shown evidence for a positive answer to both questions. But the direct evidence for brain-behavior correlations at the subcortical level is still missing. The proposed cross-language study will test Chinese-speaking and English-speaking adults to investigate Native Language Neural Commitment at the subcortical level. The investigators are interested in di
Primary Outcome
EEG signals to pitch changes in speech and nonspeech sounds are analyzed to obtain the brainstem frequency following responses (FFRs). Autocorrelation method will be applied to the FFRs to quantify each participant's brainstem pitch strength. Higher average autocorrelation value indicates greater pitch strength. This EEG measure is to see whether tonal-language speakers and nontonal language speakers differ in brainstem encoding of pitch information.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2015-07 |
| Est. Completion | 2016-12 |
What the finished NCT02774356 record still lists
NCT02774356 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 36 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT02774356 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02774356 about?
NCT02774356 is a clinical study titled "Testing Native Language Neural Commitment at the Subcortical Level". This mentored student research project is funded by the Graduate Research Partnership Program with a projected timeline for data collection in the summer of 2015. Previous research has shown that language experience alters the way the human brain processes speech information. This phenomenon takes p...
What is the current status of trial NCT02774356?
This trial is currently completed. The enrollment target is 36 participants. The study started on 2015-07. Estimated completion is 2016-12.
Who is sponsoring clinical trial NCT02774356?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
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