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NCT02682342 · ClinicalTrials.gov registry record
Hyperglycemia and Mitochondrial Function in The Endothelium of Humans
A clinical trial, sponsored by Medical College of Wisconsin.
- Completed
- Registry status
- 35
- Enrollment target
NCT02682342: Completed study, sponsored by Medical College of Wisconsin.
NCT02682342 is a clinical trial that has completed, run by Medical College of Wisconsin. The registered enrollment target is 35 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02682342 has completed, sponsored by Medical College of Wisconsin.
- COMPLETED
- Registry status
- 35 participants
- Enrollment target
Study Summary
In this study, the investigators will test the hypothesis that acute in vivo exposure to hyperglycemia increases mitochondrial network fragmentation and mitochondrial reactive oxygen species production (ROS) production in human arterial endothelial cells.
Primary Outcome
The investigators visualize the mitochondrial network complexity in these cells using our previously reported and validated immunofluorescence method using cytochrome c antibodies to tag the mitochondria. Network fragmentation (total number of fragments/ total fluorescent pixels\*100) will be quantified by network fragmentation count calculated with ImageJ (NIH, Bethesda) using a validated protocol.
Interventions
- OTHER 75 g glucose solution
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 35 participants |
| Start Date | 2016-03-09 |
| Est. Completion | 2022-11-22 |
What the finished NCT02682342 record still lists
NCT02682342 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 35 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which 75 g glucose solution is the first listed.
NCT02682342 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02682342 about?
NCT02682342 is a clinical study titled "Hyperglycemia and Mitochondrial Function in The Endothelium of Humans". In this study, the investigators will test the hypothesis that acute in vivo exposure to hyperglycemia increases mitochondrial network fragmentation and mitochondrial reactive oxygen species production (ROS) production in human arterial endothelial cells.
What is the current status of trial NCT02682342?
This trial is currently completed. The enrollment target is 35 participants. The study started on 2016-03-09. Estimated completion is 2022-11-22.
What interventions are being tested in trial NCT02682342?
The interventions under investigation include: 75 g glucose solution (OTHER).
Who is sponsoring clinical trial NCT02682342?
This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.
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