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NCT02652468 · ClinicalTrials.gov registry record · NA
TCR-α/β and CD19 Depleted Stem Cell Grafts From Haplo Donors for HSCT in Relapsed Lymphoma
A NA study of Lymphoma, sponsored by University of Wisconsin, Madison.
- Completed
- Registry status
- NA
- Development phase
- 11
- Enrollment target
- 1
- Study location
NCT02652468: Completed NA study of Lymphoma, sponsored by University of Wisconsin, Madison.
NCT02652468 is a NA study of Lymphoma that has completed, run by University of Wisconsin, Madison. The registered enrollment target is 11 participants, below the 484-participant average among 299 other Lymphoma trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02652468, a NA study of Lymphoma, has completed, sponsored by University of Wisconsin, Madison.
- COMPLETED
- Registry status
- NA
- Development phase
- 11 participants
- Enrollment target
- 1
- Study location
Study Summary
To determine engraftment of neutrophils and platelets at 28 days following alpha/beta T-cell and CD19 cell depletion using Human Leukocyte Antigen (HLA) haploidentical donors for peripheral blood stem cell transplant in relapsed lymphoma. Assess incidence of acute Graft Versus Host Disease (GVHD), chronic GVHD, graft failure rate, treatment related mortality rate, progression free survival and overall survival of patients. The stem cell product will be processed using an investigational Miltenyi cell selection device/system that removes the alpha/beta T-cells and CD19+ cells, immune system cells that are more likely to cause GVHD.
Primary Outcome
To determine engraftment of neutrophils and platelets at 28 days following alpha/beta T-cell depletion using Human Leukocyte Antigen (HLA) haploidentical donors for stem cell transplant in relapsed lymphoma.
Conditions Studied
Interventions
- DRUG Cyclophosphamide
- DRUG Mesna
- DRUG Fludarabine Phosphate
- RADIATION Total nodal irradiation
- BIOLOGICAL T Cell-Depleted Hematopoietic Stem Cell Transplantation
Study Locations (1)
Wisconsin
- University of Wisconsin Carbone Cancer Center - Madison
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 11 participants |
| Start Date | 2016-03-10 |
| Est. Completion | 2021-09-17 |
| Phase | NA |
What the finished NCT02652468 record still lists
NCT02652468 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 11 participants, a relatively small participant target, below the 484-participant average among 299 other Lymphoma trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Lymphoma appearing as the primary indexed condition, and to 5 interventions - of which Cyclophosphamide is the first listed.
NCT02652468 reports a single indexed study location in Wisconsin.
Frequently Asked Questions
What is clinical trial NCT02652468 about?
NCT02652468 is a clinical study titled "TCR-α/β and CD19 Depleted Stem Cell Grafts From Haplo Donors for HSCT in Relapsed Lymphoma". To determine engraftment of neutrophils and platelets at 28 days following alpha/beta T-cell and CD19 cell depletion using Human Leukocyte Antigen (HLA) haploidentical donors for peripheral blood stem cell transplant in relapsed lymphoma. Assess incidence of acute Graft Versus Host Disease (GVHD), ...
What is the current status of trial NCT02652468?
This trial is currently completed. It is a NA study. The enrollment target is 11 participants. The study started on 2016-03-10. Estimated completion is 2021-09-17.
What conditions does trial NCT02652468 study?
This clinical trial studies the following conditions: Lymphoma.
What interventions are being tested in trial NCT02652468?
The interventions under investigation include: Cyclophosphamide (DRUG), Mesna (DRUG), Fludarabine Phosphate (DRUG), Total nodal irradiation (RADIATION), T Cell-Depleted Hematopoietic Stem Cell Transplantation (BIOLOGICAL).
Who is sponsoring clinical trial NCT02652468?
This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02652468 being conducted?
This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT02652468's enrollment target sits among peer trials
11 273rd of 299 higher than 25 of 299 other Lymphoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Lymphoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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