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NCT02594254 · ClinicalTrials.gov registry record · Phase 2
Phase 2 Study to Evaluate the Microbiology and Safety of C16G2 Administered to Adult and Adolescent Dental Subjects
A Phase 2 study of Dental Caries, sponsored by Armata Pharmaceuticals.
- Completed
- Registry status
- Phase 2
- Development phase
- 135
- Enrollment target
- 10
- Study locations
NCT02594254: Completed Phase 2 study of Dental Caries, sponsored by Armata Pharmaceuticals.
NCT02594254 is a Phase 2 study of Dental Caries that has completed, run by Armata Pharmaceuticals. The registered enrollment target is 135 participants, below the 718-participant average among 30 other Dental Caries trials with a reported enrollment target (81% lower). The trial reports 10 study locations across 8 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02594254, a Phase 2 study of Dental Caries, has completed, sponsored by Armata Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 135 participants
- Enrollment target
- 10
- Study locations
Study Summary
The purpose of this study is to evaluate if C16G2 Gel administered over a certain period of time either with a toothbrush or a custom dental tray can effectively kill bacteria in the mouth that cause dental cavities.
Primary Outcome
To assess the targeted antimicrobial activity of C16G2 Gel applications as measured by a reduction in Streptococcus mutans in saliva and dental plaque
Conditions Studied
Interventions
- OTHER Placebo
- DRUG C16G2 Gel
Study Locations (10)
Montana
- John F. Pittaway, DMD - Kalispell
- Plaza West II Dental Group - Kalispell
Texas
- Texas Baylor College of Dentistry - Dallas
- Anthony Henegar, DDS, PA - Irving
California
- Imperial Beach Family Dentistry - Imperial Beach
Indiana
- Indiana University School of Dentistry - Indianapolis
Massachusetts
- Tufts University - Boston
New York
- New York University College of Dentistry - New York
North Carolina
- East Carolina University - Greenville
Pennsylvania
- University of Pennsylvania School of Dental Medicine - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 135 participants |
| Start Date | 2015-11 |
| Est. Completion | 2016-09 |
| Phase | Phase 2 |
What the finished NCT02594254 record still lists
NCT02594254 is an interventional study that assigns participants to a tested intervention. The registered 135 participants enrollment target is mid-sized for trials with a published cap, below the 718-participant average among 30 other Dental Caries trials with a reported enrollment target (81% lower).
The record links to 1 condition, with Dental Caries appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT02594254 lists 10 locations in 8 states (Montana, Texas, California).
Frequently Asked Questions
What is clinical trial NCT02594254 about?
NCT02594254 is a clinical study titled "Phase 2 Study to Evaluate the Microbiology and Safety of C16G2 Administered to Adult and Adolescent Dental Subjects". The purpose of this study is to evaluate if C16G2 Gel administered over a certain period of time either with a toothbrush or a custom dental tray can effectively kill bacteria in the mouth that cause dental cavities.
What is the current status of trial NCT02594254?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 135 participants. The study started on 2015-11. Estimated completion is 2016-09.
What conditions does trial NCT02594254 study?
This clinical trial studies the following conditions: Dental Caries.
What interventions are being tested in trial NCT02594254?
The interventions under investigation include: Placebo (OTHER), C16G2 Gel (DRUG).
Who is sponsoring clinical trial NCT02594254?
This trial is sponsored by Armata Pharmaceuticals, which has 11 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02594254 being conducted?
This trial has 10 study locations across California, Indiana, Massachusetts, Montana, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Dental Caries
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02594254's enrollment target sits among peer trials
135 10th of 30 higher than 21 of 30 other Dental Caries trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Dental Caries trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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