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NCT02555644 · ClinicalTrials.gov registry record · Phase 1

A Study of Prexasertib (LY2606368) With Chemotherapy and Radiation in Participants With Head and Neck Cancer

A Phase 1 study, sponsored by Eli Lilly and Company.

Completed
Registry status
Phase 1
Development phase
70
Enrollment target

NCT02555644: Completed Phase 1 study, sponsored by Eli Lilly and Company.

NCT02555644 is a Phase 1 study that has completed, run by Eli Lilly and Company. The registered enrollment target is 70 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (17% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02555644, a Phase 1 study, has completed, sponsored by Eli Lilly and Company.

COMPLETED
Registry status
Phase 1
Development phase
70 participants
Enrollment target

Study Summary

The main purpose of this study is to investigate the safety of prexasertib in combination with other anti-cancer drugs (cisplatin or cetuximab) and radiation therapy in participants with locally advanced head and neck cancer. The study has two parts (A and B). Participants will only enroll in one part.

Interventions

  • DRUG Cisplatin
  • DRUG Cetuximab
  • RADIATION Intensity Modulated Radiation Therapy
  • DRUG Prexasertib

Trial Details

FieldValue
Enrollment Target 70 participants
Start Date 2016-02-24
Est. Completion 2019-01-14
Phase Phase 1
Eli Lilly and Company

1,341 total trials

What the finished NCT02555644 record still lists

NCT02555644 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (17% higher).

The record links to 0 conditions, and to 4 interventions - of which Cisplatin is the first listed.

NCT02555644 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02555644 about?

NCT02555644 is a clinical study titled "A Study of Prexasertib (LY2606368) With Chemotherapy and Radiation in Participants With Head and Neck Cancer". The main purpose of this study is to investigate the safety of prexasertib in combination with other anti-cancer drugs (cisplatin or cetuximab) and radiation therapy in participants with locally advanced head and neck cancer. The study has two parts (A and B). Participants will only enroll in one pa...

What is the current status of trial NCT02555644?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 70 participants. The study started on 2016-02-24. Estimated completion is 2019-01-14.

What interventions are being tested in trial NCT02555644?

The interventions under investigation include: Cisplatin (DRUG), Cetuximab (DRUG), Intensity Modulated Radiation Therapy (RADIATION), Prexasertib (DRUG).

Who is sponsoring clinical trial NCT02555644?

This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02555644's enrollment target sits among peer trials

70 749th of 2000 higher than 1,227 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02555644, the US trial registry maintained by the National Library of Medicine. NCT02555644 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.