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NCT02502942 · ClinicalTrials.gov registry record · NA

Effects of Upper Airway Muscle Training on OSA

A NA study of Obstructive Sleep Apnea, sponsored by University of California, San Diego.

Completed
Registry status
NA
Development phase
134
Enrollment target
1
Study location

NCT02502942 is a NA study of Obstructive Sleep Apnea that has completed, run by University of California, San Diego. The registered enrollment target is 134 participants, below the 221-participant average among 155 other Obstructive Sleep Apnea trials with a reported enrollment target (39% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT02502942, a NA study of Obstructive Sleep Apnea, has completed, sponsored by University of California, San Diego.

COMPLETED
Registry status
NA
Development phase
134 participants
Enrollment target
1
Study location

Study Summary

Obstructive sleep apnea (OSA) is a common disorder characterized by recurrent collapse of the upper airway during sleep. OSA patients have a small upper airway that is kept patent during wakefulness by a compensatory increase in upper airway (UA) dilator muscle (e.g. genioglossus) activity. At sleep onset this compensation is reduced or lost, resulting in upper airway narrowing or collapse. Previous studies of upper airway muscle training showed variable results on OSA, but so far there has not been any practical, long-term, systematic upper airway muscle training developed or studied as the treatment of OSA. In theory, strengthening the upper airway muscle with exercise training in theory helps maintain a patent airway during sleep. Therefore, investigators aim to test the hypothesis: 1) UA muscle training can improve sleep apnea in some patients with OSA, including those already receiving treatment with PAP or oral appliance therapy. 2) Muscle training is a viable therapy for a definable subset of OSA patients. Investigators hypothesize that patients with OSA who have mild or moderately compromised upper airway anatomy will benefit the most. 3)There will be a positive association between the changes in muscle function and improvement in OSA severity.

Conditions Studied

Interventions

  • BEHAVIORAL Sham Exercise
  • BEHAVIORAL Upper Airway Muscle Exercise

Study Locations (1)

California

  • University of California, San Diego - San Diego

Trial Details

FieldValue
Enrollment Target 134 participants
Start Date 2015-08
Est. Completion 2019-06-24
Phase NA

Sponsor

University of California, San Diego

775 total trials

What the Registry Record Tells You About NCT02502942

The ClinicalTrials.gov registry entry for NCT02502942 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 134 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 221-participant average among 155 other Obstructive Sleep Apnea trials with a reported enrollment target (39% lower). The listed sponsor is University of California, San Diego, which has 775 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Obstructive Sleep Apnea appearing as the primary indexed condition, and to 2 interventions - of which Sham Exercise is the first listed.

NCT02502942 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT02502942 about?

NCT02502942 is a clinical study titled "Effects of Upper Airway Muscle Training on OSA". Obstructive sleep apnea (OSA) is a common disorder characterized by recurrent collapse of the upper airway during sleep. OSA patients have a small upper airway that is kept patent during wakefulness by a compensatory increase in upper airway (UA) dilator muscle (e.g. genioglossus) activity. At sleep...

What is the current status of trial NCT02502942?

This trial is currently completed. It is a NA study. The enrollment target is 134 participants. The study started on 2015-08. Estimated completion is 2019-06-24.

What conditions does trial NCT02502942 study?

This clinical trial studies the following conditions: Obstructive Sleep Apnea.

What interventions are being tested in trial NCT02502942?

The interventions under investigation include: Sham Exercise (BEHAVIORAL), Upper Airway Muscle Exercise (BEHAVIORAL).

Who is sponsoring clinical trial NCT02502942?

This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02502942 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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