Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT02474173 · ClinicalTrials.gov registry record · Phase 1

Onalespib and Paclitaxel in Treating Patients With Advanced Triple Negative Breast Cancer

A Phase 1 study, sponsored by National Cancer Institute (NCI).

Terminated
Registry status
Phase 1
Development phase
31
Enrollment target

NCT02474173: Clinical Trial Phase 1 study, sponsored by National Cancer Institute (NCI).

NCT02474173 is a Phase 1 study that was terminated before completion, run by National Cancer Institute (NCI). The registered enrollment target is 31 participants. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT02474173, a Phase 1 study, was terminated before completion, sponsored by National Cancer Institute (NCI).

TERMINATED
Registry status
Phase 1
Development phase
31 participants
Enrollment target

Study Summary

This phase Ib trial studies the side effects and best dose onalespib when given together with paclitaxel in treating patients with triple negative breast cancer that has spread to other places in the body and usually cannot be cured or controlled with treatment (advanced). Onalespib works by blocking proper processing of proteins that are important for cancer growth. This results in inability of these proteins to work properly. Paclitaxel kills breast cancer cells by interfering with their ability to divide. Giving onalespib together with paclitaxel may be better than giving either one alone in treating patients with breast cancer.

Interventions

  • OTHER Laboratory Biomarker Analysis
  • DRUG Paclitaxel
  • OTHER Pharmacological Study
  • DRUG Onalespib

Trial Details

FieldValue
Enrollment Target 31 participants
Start Date 2016-01-15
Est. Completion 2022-10-26
Phase Phase 1

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT02474173

The ClinicalTrials.gov registry entry for NCT02474173 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 31 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Laboratory Biomarker Analysis is the first listed.

NCT02474173 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02474173 about?

NCT02474173 is a clinical study titled "Onalespib and Paclitaxel in Treating Patients With Advanced Triple Negative Breast Cancer". This phase Ib trial studies the side effects and best dose onalespib when given together with paclitaxel in treating patients with triple negative breast cancer that has spread to other places in the body and usually cannot be cured or controlled with treatment (advanced). Onalespib works by blockin...

What is the current status of trial NCT02474173?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 31 participants. The study started on 2016-01-15. Estimated completion is 2022-10-26.

What interventions are being tested in trial NCT02474173?

The interventions under investigation include: Laboratory Biomarker Analysis (OTHER), Paclitaxel (DRUG), Pharmacological Study (OTHER), Onalespib (DRUG).

Who is sponsoring clinical trial NCT02474173?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.