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NCT02451748 · ClinicalTrials.gov registry record · Phase 4

IL-7 and IL-7R Expression in RA Patients With Active vs. Inactive Disease Treated With DMARD or CIMZIA

A Phase 4 study of Rheumatoid Arthritis, sponsored by University of Illinois at Chicago.

Completed
Registry status
Phase 4
Development phase
32
Enrollment target
1
Study location

NCT02451748: Completed Phase 4 study of Rheumatoid Arthritis, sponsored by University of Illinois at Chicago.

NCT02451748 is a Phase 4 study of Rheumatoid Arthritis that has completed, run by University of Illinois at Chicago. The registered enrollment target is 32 participants, below the 4,690-participant average among 197 other Rheumatoid Arthritis trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02451748, a Phase 4 study of Rheumatoid Arthritis, has completed, sponsored by University of Illinois at Chicago.

COMPLETED
Registry status
Phase 4
Development phase
32 participants
Enrollment target
1
Study location

Study Summary

The purpose of the study is to better understand the factors present in the cells of inflamed joints of patients with arthritis that may cause rheumatoid arthritis. Knowledge gained from this study may lead to new and better therapies for arthritis.

Primary Outcome

Expression of IL-7 and IL-7R mRNA levels measured by real-time RT-PCR.

Conditions Studied

Interventions

  • DRUG Hydroxychloroquine
  • DRUG Sulfasalazine
  • OTHER Lab Work
  • DRUG Certolizumab pegol (CDP870, tradename Cimzia)(prefilled syringes at the dose of 200mg)
  • DRUG Certolizumab pegol (CDP870, tradename Cimzia)

Study Locations (1)

Illinois

  • Outpatient Care Center - Chicago

Trial Details

FieldValue
Enrollment Target 32 participants
Start Date 2015-08
Est. Completion 2017-12
Phase Phase 4
University of Illinois at Chicago

430 total trials

What the finished NCT02451748 record still lists

NCT02451748 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 4,690-participant average among 197 other Rheumatoid Arthritis trials with a reported enrollment target (99% lower).

The record links to 1 condition, with Rheumatoid Arthritis appearing as the primary indexed condition, and to 5 interventions - of which Hydroxychloroquine is the first listed.

NCT02451748 reports a single indexed study location in Illinois.

Frequently Asked Questions

What is clinical trial NCT02451748 about?

NCT02451748 is a clinical study titled "IL-7 and IL-7R Expression in RA Patients With Active vs. Inactive Disease Treated With DMARD or CIMZIA". The purpose of the study is to better understand the factors present in the cells of inflamed joints of patients with arthritis that may cause rheumatoid arthritis. Knowledge gained from this study may lead to new and better therapies for arthritis.

What is the current status of trial NCT02451748?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 32 participants. The study started on 2015-08. Estimated completion is 2017-12.

What conditions does trial NCT02451748 study?

This clinical trial studies the following conditions: Rheumatoid Arthritis.

What interventions are being tested in trial NCT02451748?

The interventions under investigation include: Hydroxychloroquine (DRUG), Sulfasalazine (DRUG), Lab Work (OTHER), Certolizumab pegol (CDP870, tradename Cimzia)(prefilled syringes at the dose of 200mg) (DRUG), Certolizumab pegol (CDP870, tradename Cimzia) (DRUG).

Who is sponsoring clinical trial NCT02451748?

This trial is sponsored by University of Illinois at Chicago, which has 430 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02451748 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Rheumatoid Arthritis

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02451748's enrollment target sits among peer trials

32 156th of 197 higher than 40 of 197 other Rheumatoid Arthritis trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Rheumatoid Arthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02451748, the US trial registry maintained by the National Library of Medicine. NCT02451748 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.