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NCT02446223 · ClinicalTrials.gov registry record · Phase 4

Evaluate the Efficacy and Safety of Large-Scale Field-Directed Topical Therapy of Actinic Keratosis of the Chest w/Ingenol Mebutate 0.015%

A Phase 4 study, sponsored by Goldman, Butterwick, Fitzpatrick and Groff.

Completed
Registry status
Phase 4
Development phase
21
Enrollment target

NCT02446223: Completed Phase 4 study, sponsored by Goldman, Butterwick, Fitzpatrick and Groff.

NCT02446223 is a Phase 4 study that has completed, run by Goldman, Butterwick, Fitzpatrick and Groff. The registered enrollment target is 21 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02446223, a Phase 4 study, has completed, sponsored by Goldman, Butterwick, Fitzpatrick and Groff.

COMPLETED
Registry status
Phase 4
Development phase
21 participants
Enrollment target

Study Summary

Evaluate the Efficacy and Safety of Large-Scale Field-Directed Topical Therapy of Actinic Keratosis of the Chest w/Ingenol Mebutate 0.015%

Primary Outcome

The primary efficacy endpoint will be complete clearance of all clinically visible AKs and no development of any new AKs on day 59. Lesion clearance will be determined on day 59 (visit 7) by comparing pretreatment lesion count with current lesion count on day 59, with primary efficacy endpoint being clearance of all lesions in treatment field and no growth of new lesions.

Interventions

  • DRUG Inggenol Mebutate 0.015%

Trial Details

FieldValue
Enrollment Target 21 participants
Start Date 2015-01
Est. Completion 2016-09
Phase Phase 4

What the finished NCT02446223 record still lists

NCT02446223 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 21 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (96% lower).

The record links to 0 conditions, and to 1 intervention - of which Inggenol Mebutate 0.015% is the first listed.

NCT02446223 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02446223 about?

NCT02446223 is a clinical study titled "Evaluate the Efficacy and Safety of Large-Scale Field-Directed Topical Therapy of Actinic Keratosis of the Chest w/Ingenol Mebutate 0.015%". Evaluate the Efficacy and Safety of Large-Scale Field-Directed Topical Therapy of Actinic Keratosis of the Chest w/Ingenol Mebutate 0.015%

What is the current status of trial NCT02446223?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 21 participants. The study started on 2015-01. Estimated completion is 2016-09.

What interventions are being tested in trial NCT02446223?

The interventions under investigation include: Inggenol Mebutate 0.015% (DRUG).

Who is sponsoring clinical trial NCT02446223?

This trial is sponsored by Goldman, Butterwick, Fitzpatrick and Groff, which has 18 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02446223's enrollment target sits among peer trials

21 1742nd of 2000 higher than 248 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02446223, the US trial registry maintained by the National Library of Medicine. NCT02446223 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.