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NCT02385214 · ClinicalTrials.gov registry record · NA
MelmarT Melanoma Margins Trial Investigating 1cm v 2cm Wide Excision Margins for Primary Cutaneous Melanoma
A NA study of Cutaneous Melanoma by AJCC V7 Stage, sponsored by Melanoma and Skin Cancer Trials Limited.
- Active
- Registry status
- NA
- Development phase
- 400
- Enrollment target
- 20
- Study locations
NCT02385214: Active NA study of Cutaneous Melanoma by AJCC V7 Stage, sponsored by Melanoma and Skin Cancer Trials Limited.
NCT02385214 is a NA study of Cutaneous Melanoma by AJCC V7 Stage that is active but no longer recruiting, run by Melanoma and Skin Cancer Trials Limited. The registered enrollment target is 400 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (72% lower). The trial reports 20 study locations across 9 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02385214, a NA study of Cutaneous Melanoma by AJCC V7 Stage, is active but no longer recruiting, sponsored by Melanoma and Skin Cancer Trials Limited.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 400 participants
- Enrollment target
- 20
- Study locations
Study Summary
Patients with a primary invasive melanoma are recommended to undergo excision of the primary lesion with a wide margin. There is evidence that less radical margins of excision may be just as safe. This is a randomised controlled trial of 1 cm versus 2 cm margin of excision of the primary lesion for adult patients with a primary invasive cutaneous melanomas \>=1mm thick to determine differences in the rate of local recurrence and melanoma specific survival. A reduction in margins is expected to improve quality of life in patients
Primary Outcome
Time from randomisation to clinically, histologically or radiologically confirmed local recurrence of melanoma including satellite lesions and in transit metastases to regional draining lymph nodes.
Conditions Studied
Interventions
- PROCEDURE Wide Local Excision = 1cm Margin
- PROCEDURE Wide Local Excision = 2cm Margin
Study Locations (20)
Other
- Sunnybrook Health Sciences Centre - Toronto
- Sahlgrenska University Hospital - Gothenburg
- North Bristol NHS Trust - Bristol
- Cambridge University Hospitals NHS Foundation Trust - Cambridge
- Royal Devon and Exeter NHS Foundation Trust - Exeter
- St. James University Hospital - Leeds
- Royal Free London NHS Foundation Trust - London
- Imperial College Healthcare NHS Trust - London
- Norfolk and Norwich University Hospital - Norwich
England
- Hull and East Yorkshire Hospitals NHS Trust - Hull
- Guy's and St Thomas' Hospital NHS Trust - London
- The Christie NHS Foundation Trust - Manchester
Victoria
- Peter MacCallum Cancer Centre Division of Cancer Surgery - Melbourne
- Alfred Hospital - Melbourne
Pennsylvania
- Thomas Jefferson University Hospital - Philadelphia
New South Wales
- Melanoma Institute Australia - Poche Centre - North Sydney
Queensland
- Gold Coast Melanom Clinic - Coolangatta
Essex
- Mid Essex Hospital Services NHS Trust - Broomfield
Mersyside
- St Helens & Knowsley NHS Trust - St Helens
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 400 participants |
| Start Date | 2015-01-03 |
| Est. Completion | 2026-08-05 |
| Phase | NA |
What the registry record for NCT02385214 still lists
NCT02385214 is an interventional study that assigns participants to a tested intervention. The registered 400 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (72% lower).
The record links to 1 condition, with Cutaneous Melanoma by AJCC V7 Stage appearing as the primary indexed condition, and to 2 interventions - of which Wide Local Excision = 1cm Margin is the first listed.
NCT02385214 names 20 study sites across 9 states, led by Other, England, Victoria.
Frequently Asked Questions
What is clinical trial NCT02385214 about?
NCT02385214 is a clinical study titled "MelmarT Melanoma Margins Trial Investigating 1cm v 2cm Wide Excision Margins for Primary Cutaneous Melanoma". Patients with a primary invasive melanoma are recommended to undergo excision of the primary lesion with a wide margin. There is evidence that less radical margins of excision may be just as safe. This is a randomised controlled trial of 1 cm versus 2 cm margin of excision of the primary lesion for ...
What is the current status of trial NCT02385214?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 400 participants. The study started on 2015-01-03. Estimated completion is 2026-08-05.
What conditions does trial NCT02385214 study?
This clinical trial studies the following conditions: Cutaneous Melanoma by AJCC V7 Stage.
What interventions are being tested in trial NCT02385214?
The interventions under investigation include: Wide Local Excision = 1cm Margin (PROCEDURE), Wide Local Excision = 2cm Margin (PROCEDURE).
Who is sponsoring clinical trial NCT02385214?
This trial is sponsored by Melanoma and Skin Cancer Trials Limited, which has 3 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02385214 being conducted?
This trial has 20 study locations across Pennsylvania, New South Wales, Queensland, Victoria, England. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cutaneous Melanoma by AJCC V7 Stage
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02385214's enrollment target sits among peer trials
400 246th of 2000 higher than 1,734 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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