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NCT02371135 · ClinicalTrials.gov registry record
Metagenomic Evaluation of the Gut Microbiome in Patients With Lynch Syndrome and Other Hereditary Colonic Polyposis Syndromes
A clinical trial of Lynch Syndrome and Hereditary Colonic Polyposis Syndromes, sponsored by Memorial Sloan Kettering Cancer Center.
- Active
- Registry status
- 77
- Enrollment target
- 1
- Study location
NCT02371135: Active study of Lynch Syndrome and Hereditary Colonic Polyposis Syndromes, sponsored by Memorial Sloan Kettering Cancer Center.
NCT02371135 is a study of Lynch Syndrome and Hereditary Colonic Polyposis Syndromes that is active but no longer recruiting, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 77 participants, below the 2,313-participant average among 21 other Lynch Syndrome trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02371135, a study of Lynch Syndrome and Hereditary Colonic Polyposis Syndromes, is active but no longer recruiting, sponsored by Memorial Sloan Kettering Cancer Center.
- ACTIVE NOT RECRUITING
- Registry status
- 77 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to understand the role bacteria that normally live in the colon may play in colorectal cancer risk, in addition to the hereditary risk to colorectal cancer. The investigators will collect stool specimens as well as additional colon biopsy specimens during the patient's scheduled colonoscopy procedure. The investigators will also collect a questionnaire about diet and lifestyle. The samples will be used to study the impact of diet on naturally-occurring oral and gut bacteria and their influences on human health including risk of cancer.
Primary Outcome
with risk of adenoma or cancer in Lynch syndrome and other hereditary colonic polyposis syndrome patients. To validate said associations, individual questions from the Brief Diet and Lifestyle Questionnaire will be primarily used in the overall analyses.
Conditions Studied
Interventions
- GENETIC colonic biopsies
- GENETIC questionnaires
Study Locations (1)
New York
- Memorial Sloan Kettering Cancer Center - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 77 participants |
| Start Date | 2015-02 |
| Est. Completion | 2027-02 |
What the registry record for NCT02371135 still lists
NCT02371135 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 77 participants, a relatively small participant target, below the 2,313-participant average among 21 other Lynch Syndrome trials with a reported enrollment target (97% lower).
The record links to 2 conditions, with Lynch Syndrome appearing as the primary indexed condition, and to 2 interventions - of which colonic biopsies is the first listed.
NCT02371135 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT02371135 about?
NCT02371135 is a clinical study titled "Metagenomic Evaluation of the Gut Microbiome in Patients With Lynch Syndrome and Other Hereditary Colonic Polyposis Syndromes". The purpose of this study is to understand the role bacteria that normally live in the colon may play in colorectal cancer risk, in addition to the hereditary risk to colorectal cancer. The investigators will collect stool specimens as well as additional colon biopsy specimens during the patient's s...
What is the current status of trial NCT02371135?
This trial is currently active not recruiting. The enrollment target is 77 participants. The study started on 2015-02. Estimated completion is 2027-02.
What conditions does trial NCT02371135 study?
This clinical trial studies the following conditions: Lynch Syndrome, Hereditary Colonic Polyposis Syndromes.
What interventions are being tested in trial NCT02371135?
The interventions under investigation include: colonic biopsies (GENETIC), questionnaires (GENETIC).
Who is sponsoring clinical trial NCT02371135?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02371135 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Lynch Syndrome
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02371135's enrollment target sits among peer trials
77 17th of 21 higher than 5 of 21 other Lynch Syndrome trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Lynch Syndrome trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
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