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NCT02348749 · ClinicalTrials.gov registry record · Phase 1

18F-MFBG Imaging for Evaluation of Neuroendocrine Malignancies

A Phase 1 study of Neuroendocrine Tumors, sponsored by Memorial Sloan Kettering Cancer Center.

Completed
Registry status
Phase 1
Development phase
48
Enrollment target
1
Study location

NCT02348749: Completed Phase 1 study of Neuroendocrine Tumors, sponsored by Memorial Sloan Kettering Cancer Center.

NCT02348749 is a Phase 1 study of Neuroendocrine Tumors that has completed, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 48 participants, below the 179-participant average among 52 other Neuroendocrine Tumors trials with a reported enrollment target (73% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02348749, a Phase 1 study of Neuroendocrine Tumors, has completed, sponsored by Memorial Sloan Kettering Cancer Center.

COMPLETED
Registry status
Phase 1
Development phase
48 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to see how a new tracer named 18F-MFBG (Meta Fluorobenzyl Guanidine) behaves in the body after injection, how it spreads to all the organs and how it is removed from the body. We will also study how long 18F-MFBG lasts in the blood after administered. In addition we want to study if 18F-MFBG can show Neuroendocrine tumors on a PET-CT or PET MR scan.

Primary Outcome

in two cohorts of patients: (a) those with NB and (b) those with non-NB NE. Data will be derived from blood draws and PET/CT scans at multiple time points after injection of 18F-MFBG IV.

Conditions Studied

Interventions

  • OTHER Blood draws
  • RADIATION 18F-MFBG (meta-fluoro benzylguanidine)
  • DEVICE Positron emission tomography (PET) imaging

Study Locations (1)

New York

  • Memorial Sloan Kettering Cancer Center - New York

Trial Details

FieldValue
Enrollment Target 48 participants
Start Date 2015-01
Est. Completion 2025-03-17
Phase Phase 1
Memorial Sloan Kettering Cancer Center

1,884 total trials

What the finished NCT02348749 record still lists

NCT02348749 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 179-participant average among 52 other Neuroendocrine Tumors trials with a reported enrollment target (73% lower).

The record links to 1 condition, with Neuroendocrine Tumors appearing as the primary indexed condition, and to 3 interventions - of which Blood draws is the first listed.

NCT02348749 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT02348749 about?

NCT02348749 is a clinical study titled "18F-MFBG Imaging for Evaluation of Neuroendocrine Malignancies". The purpose of this study is to see how a new tracer named 18F-MFBG (Meta Fluorobenzyl Guanidine) behaves in the body after injection, how it spreads to all the organs and how it is removed from the body. We will also study how long 18F-MFBG lasts in the blood after administered. In addition we want...

What is the current status of trial NCT02348749?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 48 participants. The study started on 2015-01. Estimated completion is 2025-03-17.

What conditions does trial NCT02348749 study?

This clinical trial studies the following conditions: Neuroendocrine Tumors.

What interventions are being tested in trial NCT02348749?

The interventions under investigation include: Blood draws (OTHER), 18F-MFBG (meta-fluoro benzylguanidine) (RADIATION), Positron emission tomography (PET) imaging (DEVICE).

Who is sponsoring clinical trial NCT02348749?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02348749 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Neuroendocrine Tumors

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02348749's enrollment target sits among peer trials

48 33rd of 52 higher than 20 of 52 other Neuroendocrine Tumors trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Neuroendocrine Tumors trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02348749, the US trial registry maintained by the National Library of Medicine. NCT02348749 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.