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NCT02341508 · ClinicalTrials.gov registry record · Phase 1
A Phase 1a, Double-Blind, Placebo-Controlled, Single Ascending Dose Study to Evaluate Lpathomab in Healthy Volunteers
A Phase 1 study, sponsored by Lpath.
- Completed
- Registry status
- Phase 1
- Development phase
- 36
- Enrollment target
NCT02341508: Completed Phase 1 study, sponsored by Lpath.
NCT02341508 is a Phase 1 study that has completed, run by Lpath. The registered enrollment target is 36 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02341508, a Phase 1 study, has completed, sponsored by Lpath.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 36 participants
- Enrollment target
Study Summary
The primary purpose of this study is to evaluate the safety and tolerability of Lpathomab in healthy volunteers. Additional endpoints include characterization of the pharmacokinetic (PK), pharmacodynamic (PD), and immunogenicity profiles of a single IV dose of Lpathomab in healthy volunteers.
Interventions
- BIOLOGICAL 0.5 mg/kg Lpathomab
- BIOLOGICAL 1.0 mg/kg Lpathomab
- BIOLOGICAL 3.0 mg/kg Lpathomab
- BIOLOGICAL 10 mg/kg Lpathomab
- BIOLOGICAL 20 mg/kg Lpathomab
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2015-09 |
| Est. Completion | 2016-03 |
| Phase | Phase 1 |
What the finished NCT02341508 record still lists
NCT02341508 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% lower).
The record links to 0 conditions, and to 5 interventions - of which 0.5 mg/kg Lpathomab is the first listed.
NCT02341508 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02341508 about?
NCT02341508 is a clinical study titled "A Phase 1a, Double-Blind, Placebo-Controlled, Single Ascending Dose Study to Evaluate Lpathomab in Healthy Volunteers". The primary purpose of this study is to evaluate the safety and tolerability of Lpathomab in healthy volunteers. Additional endpoints include characterization of the pharmacokinetic (PK), pharmacodynamic (PD), and immunogenicity profiles of a single IV dose of Lpathomab in healthy volunteers.
What is the current status of trial NCT02341508?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2015-09. Estimated completion is 2016-03.
What interventions are being tested in trial NCT02341508?
The interventions under investigation include: 0.5 mg/kg Lpathomab (BIOLOGICAL), 1.0 mg/kg Lpathomab (BIOLOGICAL), 3.0 mg/kg Lpathomab (BIOLOGICAL), 10 mg/kg Lpathomab (BIOLOGICAL), 20 mg/kg Lpathomab (BIOLOGICAL).
Who is sponsoring clinical trial NCT02341508?
This trial is sponsored by Lpath, which has 5 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02341508's enrollment target sits among peer trials
36 1210th of 2000 higher than 743 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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