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NCT02339324 · ClinicalTrials.gov registry record · Phase 1

Neoadjuvant Combination Biotherapy With Pembrolizumab and High Dose IFN-alfa2b

A Phase 1 study, sponsored by Yana Najjar.

Completed
Registry status
Phase 1
Development phase
31
Enrollment target

NCT02339324 is a Phase 1 study that has completed, run by Yana Najjar. The registered enrollment target is 31 participants.

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The verdict

NCT02339324, a Phase 1 study, has completed, sponsored by Yana Najjar.

COMPLETED
Registry status
Phase 1
Development phase
31 participants
Enrollment target

Study Summary

This study plans to to estimate the safety profile of the combination biotherapy regimen consisting of standard-dose interferon alpha-2b (HDI) and anti-PD1 monoclonal antibody, Pembrolizumab, for the neoadjuvant therapy of locally/regionally advanced/recurrent melanoma. Also, the objectives of this trial include the evaluation of prognostic and predictive biomarkers, radiologic preoperative response rate, pathologic response rate, progression free survival and overall survival. Up to 30 evaluable patients will be accrued.

Interventions

  • DRUG Pembrolizumab and high dose interferon alfa-2b (HDI)

Trial Details

FieldValue
Enrollment Target 31 participants
Start Date 2015-03-06
Est. Completion 2019-11-02
Phase Phase 1

Sponsor

Yana Najjar

8 total trials

What the Registry Record Tells You About NCT02339324

The ClinicalTrials.gov registry entry for NCT02339324 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 31 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Yana Najjar, which has 8 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Pembrolizumab and high dose interferon alfa-2b (HDI) is the first listed.

NCT02339324 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02339324 about?

NCT02339324 is a clinical study titled "Neoadjuvant Combination Biotherapy With Pembrolizumab and High Dose IFN-alfa2b". This study plans to to estimate the safety profile of the combination biotherapy regimen consisting of standard-dose interferon alpha-2b (HDI) and anti-PD1 monoclonal antibody, Pembrolizumab, for the neoadjuvant therapy of locally/regionally advanced/recurrent melanoma. Also, the objectives of this ...

What is the current status of trial NCT02339324?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 31 participants. The study started on 2015-03-06. Estimated completion is 2019-11-02.

What interventions are being tested in trial NCT02339324?

The interventions under investigation include: Pembrolizumab and high dose interferon alfa-2b (HDI) (DRUG).

Who is sponsoring clinical trial NCT02339324?

This trial is sponsored by Yana Najjar, which has 8 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.