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NCT02315729 · ClinicalTrials.gov registry record
Analysis of Prognostic Cell Signaling Factors in Adolescent Idiopathic Scoliosis
A clinical trial of Adolescent Idiopathic Scoliosis, sponsored by University of Colorado, Denver.
- Recruiting
- Registry status
- 380
- Enrollment target
- 1
- Study location
NCT02315729: Recruiting study of Adolescent Idiopathic Scoliosis, sponsored by University of Colorado, Denver.
NCT02315729 is a study of Adolescent Idiopathic Scoliosis that is actively recruiting participants, run by University of Colorado, Denver. The registered enrollment target is 380 participants, above the 224-participant average among 7 other Adolescent Idiopathic Scoliosis trials with a reported enrollment target (70% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02315729, a study of Adolescent Idiopathic Scoliosis, is actively recruiting participants, sponsored by University of Colorado, Denver.
- RECRUITING
- Registry status
- 380 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to identify potential markers for curve progression in adolescent idiopathic scoliosis (AIS). Despite its prevalence and impact on child health, the etiology of AIS and molecular mechanisms underlying its development and progression remain poorly understood. Clinical criteria and features cannot adequately predict which children, diagnosed with mild disease, will undergo subsequent curve progression requiring intervention. The investigators hypothesize that alterations in specific genetic markers will be correlated with the progression of AIS curves over time. Thus, these markers could be used in the future to develop a reliable, inexpensive and relatively non-invasive cell based diagnostic test to (1) predict spinal curve progression in AIS, (2) select patients likely to benefit from early surgical intervention, and (3) potentially screen for asymptomatic children at risk of developing idiopathic scoliosis.
Primary Outcome
Cobb angle, disc wedging, vertebral body wedging, coronal balance, sagittal balance
Conditions Studied
Study Locations (1)
Colorado
- Children'S Hospital of Colorado - Denver
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 380 participants |
| Start Date | 2016-11 |
| Est. Completion | 2028-12 |
What NCT02315729 shows while recruiting
NCT02315729 is an observational study that tracks outcomes without assigning an intervention. The registered 380 participants enrollment target is mid-sized for trials with a published cap, above the 224-participant average among 7 other Adolescent Idiopathic Scoliosis trials with a reported enrollment target (70% higher).
The record links to 1 condition, with Adolescent Idiopathic Scoliosis appearing as the primary indexed condition, and to 0 interventions.
NCT02315729 reports a single indexed study location in Colorado.
Frequently Asked Questions
What is clinical trial NCT02315729 about?
NCT02315729 is a clinical study titled "Analysis of Prognostic Cell Signaling Factors in Adolescent Idiopathic Scoliosis". The purpose of this study is to identify potential markers for curve progression in adolescent idiopathic scoliosis (AIS). Despite its prevalence and impact on child health, the etiology of AIS and molecular mechanisms underlying its development and progression remain poorly understood. Clinical cri...
What is the current status of trial NCT02315729?
This trial is currently recruiting. The enrollment target is 380 participants. The study started on 2016-11. Estimated completion is 2028-12.
What conditions does trial NCT02315729 study?
This clinical trial studies the following conditions: Adolescent Idiopathic Scoliosis.
Who is sponsoring clinical trial NCT02315729?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02315729 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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