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NCT02301143 · ClinicalTrials.gov registry record · Phase 2

Phase 2 Nab® -Paclitaxel (Abraxane®) Plus Gemcitabine in Subjects With Locally Advanced Pancreatic Cancer (LAPC)

A Phase 2 study, sponsored by Celgene.

Completed
Registry status
Phase 2
Development phase
107
Enrollment target

NCT02301143: Completed Phase 2 study, sponsored by Celgene.

NCT02301143 is a Phase 2 study that has completed, run by Celgene. The registered enrollment target is 107 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (20% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02301143, a Phase 2 study, has completed, sponsored by Celgene.

COMPLETED
Registry status
Phase 2
Development phase
107 participants
Enrollment target

Study Summary

This clinical study is in subjects who are 18 years old or older with locally advanced pancreatic cancer who have not received prior treatment for their pancreatic cancer. The study treats all subjects with nab-Paclitaxel plus gemcitabine for approximately 6 months of treatment. Subjects who complete the treatment will choose, with their treating physicians, what additional treatment should be given: more nab-Paclitaxel plus gemcitabine, Chemoradiation therapy, or surgery to treat the locally advanced pancreatic cancer.

Primary Outcome

TTF was defined as the time after the first dose of study therapy to discontinuation of study therapy due to disease progression, death by any cause, or the start of a new non-protocol-defined anticancer therapy/surgery. If a participant does not progress, die or start a new non-protocol-defined anticancer therapy, the participant was censored on the last tumor assessment date. Tumor evaluations of CT or MRI scans were assessed by the investigative sites and response determined according to Res

Interventions

  • DRUG Capecitabine
  • DRUG Gemcitabine
  • PROCEDURE Surgery
  • DRUG nab-Paclitaxel
  • DRUG Chemoradiation

Trial Details

FieldValue
Enrollment Target 107 participants
Start Date 2015-04-21
Est. Completion 2018-04-26
Phase Phase 2
Celgene

308 total trials

What the finished NCT02301143 record still lists

NCT02301143 is an interventional study that assigns participants to a tested intervention. The registered 107 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (20% lower).

The record links to 0 conditions, and to 5 interventions - of which Capecitabine is the first listed.

NCT02301143 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02301143 about?

NCT02301143 is a clinical study titled "Phase 2 Nab® -Paclitaxel (Abraxane®) Plus Gemcitabine in Subjects With Locally Advanced Pancreatic Cancer (LAPC)". This clinical study is in subjects who are 18 years old or older with locally advanced pancreatic cancer who have not received prior treatment for their pancreatic cancer. The study treats all subjects with nab-Paclitaxel plus gemcitabine for approximately 6 months of treatment. Subjects who complet...

What is the current status of trial NCT02301143?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 107 participants. The study started on 2015-04-21. Estimated completion is 2018-04-26.

What interventions are being tested in trial NCT02301143?

The interventions under investigation include: Capecitabine (DRUG), Gemcitabine (DRUG), Surgery (PROCEDURE), nab-Paclitaxel (DRUG), Chemoradiation (DRUG).

Who is sponsoring clinical trial NCT02301143?

This trial is sponsored by Celgene, which has 308 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02301143's enrollment target sits among peer trials

107 646th of 2000 higher than 1,353 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02301143, the US trial registry maintained by the National Library of Medicine. NCT02301143 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.