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NCT02301117 · ClinicalTrials.gov registry record · Phase 1
A Phase I Study of TAS-102 in Patients With Advanced Solid Tumors With Renal Impairment
A Phase 1 study of Advanced Solid Tumors, sponsored by Taiho Oncology.
- Completed
- Registry status
- Phase 1
- Development phase
- 43
- Enrollment target
- 14
- Study locations
NCT02301117: Completed Phase 1 study of Advanced Solid Tumors, sponsored by Taiho Oncology.
NCT02301117 is a Phase 1 study of Advanced Solid Tumors that has completed, run by Taiho Oncology. The registered enrollment target is 43 participants, below the 198-participant average among 144 other Advanced Solid Tumors trials with a reported enrollment target (78% lower). The trial reports 14 study locations across 9 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02301117, a Phase 1 study of Advanced Solid Tumors, has completed, sponsored by Taiho Oncology.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 43 participants
- Enrollment target
- 14
- Study locations
Study Summary
Study to evaluate the safety, tolerability, and pharmacokinetics of TAS-102 in patients with advanced solid tumors and varying degrees of renal impairment.
Primary Outcome
FTD, FTY and TPI: pharmacokinetic parameters Cmax, Tmax, AUC0-last, AUC0-inf, and T1/2. FTD, FTY, and TPI: Ae% and CLr. FTD and TPI: CL/F, Vd/F of TAS-102
Conditions Studied
Interventions
- DRUG TAS-102
Study Locations (14)
Other
- Brno Clinical Site - Brno
- Praha Clinical Site - Prague
- Belgrade Clinical Site - Belgrade
- Sremska Kamenica Clinical Site - Kamenitz
California
- Duarte Clinical Site - Duarte
- Santa Monica Clinical Site - Santa Monica
Ohio
- Cleveland Clinical Site - Cleveland
- Cleveland Clinical Site - Cleveland
Arizona
- Phoenix Clinical Site - Phoenix
Florida
- Gainesville Clinical Site - Gainesville
Maryland
- Baltimore Clinical Site - Baltimore
Massachusetts
- Boston Clinical Site - Boston
Pennsylvania
- Pittsburgh Clinical Site - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 43 participants |
| Start Date | 2015-01 |
| Est. Completion | 2019-06-19 |
| Phase | Phase 1 |
What the finished NCT02301117 record still lists
NCT02301117 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 43 participants, a relatively small participant target, below the 198-participant average among 144 other Advanced Solid Tumors trials with a reported enrollment target (78% lower).
The record links to 1 condition, with Advanced Solid Tumors appearing as the primary indexed condition, and to 1 intervention - of which TAS-102 is the first listed.
NCT02301117 lists 14 locations in 9 states (Other, California, Ohio).
Frequently Asked Questions
What is clinical trial NCT02301117 about?
NCT02301117 is a clinical study titled "A Phase I Study of TAS-102 in Patients With Advanced Solid Tumors With Renal Impairment". Study to evaluate the safety, tolerability, and pharmacokinetics of TAS-102 in patients with advanced solid tumors and varying degrees of renal impairment.
What is the current status of trial NCT02301117?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 43 participants. The study started on 2015-01. Estimated completion is 2019-06-19.
What conditions does trial NCT02301117 study?
This clinical trial studies the following conditions: Advanced Solid Tumors.
What interventions are being tested in trial NCT02301117?
The interventions under investigation include: TAS-102 (DRUG).
Who is sponsoring clinical trial NCT02301117?
This trial is sponsored by Taiho Oncology, which has 52 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02301117 being conducted?
This trial has 14 study locations across Arizona, California, Florida, Maryland, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Advanced Solid Tumors
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02301117's enrollment target sits among peer trials
43 108th of 144 higher than 37 of 144 other Advanced Solid Tumors trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Advanced Solid Tumors trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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