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NCT02276417 · ClinicalTrials.gov registry record
PICS: Subtitle Cardiac Dysfunction in Older Sepsis Survivors
A clinical trial of Sepsis, sponsored by University of Florida.
- Active
- Registry status
- 668
- Enrollment target
- 1
- Study location
NCT02276417: Active study of Sepsis, sponsored by University of Florida.
NCT02276417 is a study of Sepsis that is active but no longer recruiting, run by University of Florida. The registered enrollment target is 668 participants, below the 6,557-participant average among 90 other Sepsis trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02276417, a study of Sepsis, is active but no longer recruiting, sponsored by University of Florida.
- ACTIVE NOT RECRUITING
- Registry status
- 668 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to define the natural history and causes of chronic critical illness (CCI) in surgical intensive care patients who have had sepsis. The investigator also wants to define the long-term physical and cognitive outcomes of this disease. The investigator will be looking at many clinical variables to try to define CCI.
Primary Outcome
Participant's blood will be analyzed for a persistent inflammatory state, anemia and adaptive immunosuppression. To look at whether sepsis alters the angiogenic balance between angiotensin II (ANGII), erythropoietin, and the VEGF receptor (VEGFR), and whether this imbalance is required for myeloid-derived suppressor cell (MDSC) expansion and chronic critical illness (CCI) and catabolism syndrome (PICS) development.
Conditions Studied
Interventions
- OTHER Blood collection
- OTHER Quality-of-life Questionnaires
- OTHER Urine collection
- OTHER Bioimpedance Analysis
- OTHER Cognitive Function Tests
Study Locations (1)
Florida
- UF Health Shands Hospital - Gainesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 668 participants |
| Start Date | 2015-01 |
| Est. Completion | 2026-07-24 |
What the registry record for NCT02276417 still lists
NCT02276417 is an observational study that tracks outcomes without assigning an intervention. The registered 668 participants enrollment target is mid-sized for trials with a published cap, below the 6,557-participant average among 90 other Sepsis trials with a reported enrollment target (90% lower).
The record links to 1 condition, with Sepsis appearing as the primary indexed condition, and to 5 interventions - of which Blood collection is the first listed.
NCT02276417 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT02276417 about?
NCT02276417 is a clinical study titled "PICS: Subtitle Cardiac Dysfunction in Older Sepsis Survivors". The purpose of this study is to define the natural history and causes of chronic critical illness (CCI) in surgical intensive care patients who have had sepsis. The investigator also wants to define the long-term physical and cognitive outcomes of this disease. The investigator will be looking at ma...
What is the current status of trial NCT02276417?
This trial is currently active not recruiting. The enrollment target is 668 participants. The study started on 2015-01. Estimated completion is 2026-07-24.
What conditions does trial NCT02276417 study?
This clinical trial studies the following conditions: Sepsis.
What interventions are being tested in trial NCT02276417?
The interventions under investigation include: Blood collection (OTHER), Quality-of-life Questionnaires (OTHER), Urine collection (OTHER), Bioimpedance Analysis (OTHER), Cognitive Function Tests (OTHER).
Who is sponsoring clinical trial NCT02276417?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02276417 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Sepsis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02276417's enrollment target sits among peer trials
668 21st of 90 higher than 70 of 90 other Sepsis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Sepsis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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